CAS 2072057-18-0

(6R)-6,7-Dihydro-10-methoxy-9-(3-methoxypropoxy)-6-(1-methylethyl)-2-oxo-2H-benzo[a]quinolizine-3-carboxylic acid

Description:

The chemical substance known as (6R)-6,7-Dihydro-10-methoxy-9-(3-methoxypropoxy)-6-(1-methylethyl)-2-oxo-2H-benzo[a]quinolizine-3-carboxylic acid, with the CAS number 2072057-18-0, is a complex organic compound characterized by its unique structural features. It contains a benzoquinolizine core, which is a bicyclic structure that contributes to its potential biological activity. The presence of multiple functional groups, including methoxy and carboxylic acid moieties, suggests that this compound may exhibit polar characteristics, influencing its solubility and reactivity. The stereochemistry indicated by the (6R) designation implies specific spatial arrangements that can affect the compound's interactions with biological targets. Additionally, the presence of an isopropyl group and a propoxy chain may enhance its lipophilicity, potentially impacting its pharmacokinetic properties. Overall, this compound's intricate structure and functional groups suggest it may have applications in medicinal chemistry, possibly as a lead compound for drug development, although specific biological activities would require further investigation.

Formula: C₂₂H₂₇NO₆

InChI: InChI=1S/C22H27NO6/c1-13(2)17-8-14-9-21(29-7-5-6-27-3)20(28-4)10-15(14)18-11-19(24)16(22(25)26)12-23(17)18/h9-13,17H,5-8H2,1-4H3,(H,25,26)/t17-/m1/s1

InChI key: InChIKey=KBXLMOYQNDMHQT-QGZVFWFLSA-N

SMILES: C(C)(C)[C@@H]1N2C(C=3C(C1)=CC(OCCCOC)=C(OC)C3)=CC(=O)C(C(O)=O)=C2

Synonyms:

• 2H-Benzo[a]quinolizine-3-carboxylic acid, 6,7-dihydro-10-methoxy-9-(3-methoxypropoxy)-6-(1-methylethyl)-2-oxo-, (6R)-
• (6R)-6,7-Dihydro-10-methoxy-9-(3-methoxypropoxy)-6-(1-methylethyl)-2-oxo-2H-benzo[a]quinolizine-3-carboxylic acid

(6R)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6,7-dihydrobenzo[A]quinolizine-3-carboxylic acid

CAS: 2072057-18-0

(6R)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6,7-dihydrobenzo[A]quinolizine-3-carboxylic acid binds to the GABAA receptor. It inhibits the binding of GABA and benzodiazepines and thus prevents the opening of chloride channels. This results in an increase in the neuronal activity of these neurons. (6R)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo - 6,7 - dihydrobenzo[A]quinolizine - 3 - carboxylic acid can be used as a research tool for studying protein interactions and activators as well as a ligand for receptors.

Formula: C₂₂H₂₇NO₆

Purity: Min. 95%

Molecular weight: 401.5 g/mol

Ref: 3D-XHD05718