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CAS 2072145-29-8

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2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine

Description:
2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine is a modified nucleoside analog that features a fluorine atom at the 2' position of the ribose sugar, which distinguishes it from the natural nucleoside guanosine. This modification can influence its biological activity, stability, and interaction with nucleic acids. The presence of the fluorine atom enhances resistance to enzymatic degradation, making it a potential candidate for therapeutic applications, particularly in antiviral and anticancer research. The compound retains the guanine base, which is essential for its role in nucleic acid synthesis and function. Its structural characteristics allow it to participate in base pairing, albeit with altered kinetics compared to its unmodified counterparts. The unique properties of 2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine make it a valuable tool in molecular biology and medicinal chemistry, where it can be utilized to study nucleic acid processes or develop new therapeutic agents. As a nucleoside analog, it may also exhibit specific interactions with enzymes involved in nucleic acid metabolism, further expanding its potential applications in research and medicine.
Formula:C10H12FN5O4
Synonyms:
  • 9-(2'-Deoxy-2'-fluoro-a-D-arabinofuranosyl)guanine
  • 2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine
  • 2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine
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Found 2 products.
  • 2'-Deoxy-2'-fluoro-α-D-arabinoguanosine
    Targetmol
    + Info

    2'-Deoxy-2'-fluoro-α-D-arabinoguanosine

    CAS:
    <p>Nucleoside Derivatives –Alpha-Nucleosides; Fluoro-modified nucleosides, Arabino-nucleosides, 2’-Modified nucleosides</p>
    Formula:C10H12FN5O4
    Color and Shape:Solid
    Molecular weight:285.23

    Ref: TM-TNU0880

  • 9-(2'-Deoxy-2'-fluoro-a-D-arabinofuranosyl)guanine
    Biosynth
    + Info

    9-(2'-Deoxy-2'-fluoro-a-D-arabinofuranosyl)guanine

    CAS:
    <p>9-(2'-Deoxy-2'-fluoro-a-D-arabinofuranosyl)guanine is a synthetic nucleoside that is effective against viral and cancer cells. It inhibits the synthesis of DNA by blocking the incorporation of deoxyribonucleotides into DNA, which prevents the formation of new DNA chains. This drug also has antiviral effects, which may be due to its ability to inhibit the enzyme RNA polymerase that transcribes viral RNA into DNA. 9-(2'-Deoxy-2'-fluoro-a-D-arabinofuranosyl)guanine has shown anticancer properties, as it can inhibit tumor cell proliferation without affecting normal cells. This drug is not active against human erythrocytes (red blood cells).</p>
    Purity:Min. 95%

    Ref: 3D-ND162896

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