CAS 2072145-33-4

3'-Azido-3'-deoxy-5'-iodouridine

Description:

3'-Azido-3'-deoxy-5'-iodouridine is a nucleoside analog that features an azido group at the 3' position and a deoxy sugar moiety, making it structurally similar to thymidine. The presence of the iodine atom at the 5' position enhances its potential for biological activity, particularly in antiviral applications. This compound is of interest in medicinal chemistry and virology due to its ability to inhibit viral replication, particularly in retroviruses like HIV. The azido group contributes to its reactivity and potential for incorporation into nucleic acids, which can disrupt normal cellular processes. As a synthetic derivative, it is not naturally occurring and is typically produced in laboratory settings for research purposes. Its unique structure allows for various modifications that can lead to different pharmacological properties, making it a valuable compound in the development of antiviral therapies. Safety and handling precautions are essential when working with this compound, as with many nucleoside analogs, due to potential toxicity and biological effects.

Formula: C₉H₁₀IN₅O₅

Synonyms:

• 3'-Azido-3'-deoxy-5'-iodouridine

3'-Azido-3'-deoxy-5-iodouridine

CAS: 2072145-33-4

Nucleoside Derivatives –Azido-nucleosides, Halo-nucleosides, 3’-Modified nucleosides, 5-Modified pyrimidine nucleosides; Scaffolds and Templates

Formula: C₉H₁₀IN₅O₅

Color and Shape: Solid

Molecular weight: 395.11

Ref: TM-TNU0132

3’-Azido-3’-deoxy-5-iodouridine

CAS: 2072145-33-4

3’-Azido-3’-deoxy-5-iodouridine is a novel antiviral nucleoside phosphoramidite. It is an activator of the NNRTI class of drugs, which inhibit the reverse transcriptase enzyme that is responsible for HIV replication. 3’-Azido-3’-deoxy-5-iodouridine has been shown to have a high quality and purity with a long shelf life. This compound is useful in the synthesis of diphosphate, monophosphate, and ribonucleosides.

Purity: Min. 95%

Ref: 3D-NA162865