The chemical substance known as (-)-3(S)-Phenyl-4(R)-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-3,4-dihydro-2H-1-benzopyran-7-ol, with the CAS number 207277-66-5, is a complex organic compound characterized by its multi-ring structure and specific stereochemistry. It features a benzopyran core, which is a fused ring system that includes a benzene ring and a pyran ring, contributing to its potential biological activity. The presence of a phenyl group and a pyrrolidinyl moiety suggests that it may interact with various biological targets, possibly influencing neurotransmitter systems or other cellular pathways. The compound's stereochemistry, indicated by the (S) and (R) designations, is crucial for its biological activity, as the spatial arrangement of atoms can significantly affect how the molecule interacts with receptors or enzymes. Additionally, the ethoxy group enhances its solubility and may influence its pharmacokinetic properties. Overall, this compound may have applications in medicinal chemistry, particularly in the development of therapeutic agents.

(-)-3(S)-Phenyl-4(R)-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-3,4-dihydro-2H-1-benzopyran-7-ol

207277-66-5: The chemical substance known as (-)-3(S)-Phenyl-4(R)-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-3,4-dihydro-2H-1-benzopyran-7-ol, with the CAS number 207277-66-5, is a complex organic compound characterized by its multi-ring structure and specific stereochemistry. It features a benzopyran core, which is a fused ring system that includes a benzene ring and a pyran ring, contributing to its potential biological activity. The presence of a phenyl group and a pyrrolidinyl moiety suggests that it may interact with various biological targets, possibly influencing neurotransmitter systems or other cellular pathways. The compound's stereochemistry, indicated by the (S) and (R) designations, is crucial for its biological activity, as the spatial arrangement of atoms can significantly affect how the molecule interacts with receptors or enzymes. Additionally, the ethoxy group enhances its solubility and may influence its pharmacokinetic properties. Overall, this compound may have applications in medicinal chemistry, particularly in the development of therapeutic agents.

<p>NNC45-0781 is a potent and selective activator of the GABAA receptor. It is a peptide, which binds to the GABA binding site on the GABAA receptor. NNC45-0781 has been shown to inhibit the growth of cells that are resistant to anti-cancer drugs, such as temozolomide, in vitro and in vivo. NNC45-0781 binds to these cells by activating the GABAA receptor, leading to cell death by inhibiting protein synthesis.</p>

NNC45-0781

<p>NNC45-0781 is a tissue-selective partial-agonist of estrogen.</p>

CAS 207277-66-5

(-)-3(S)-Phenyl-4(R)-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-3,4-dihydro-2H-1-benzopyran-7-ol

NNC45-0781

Ref: 3D-HIA27766

NNC45-0781

Ref: TM-T12239