CAS 20734-58-1

Proton sponge

Description:

Proton sponge, scientifically known as 1,8-bis(dimethylamino)naphthalene, is a chemical compound characterized by its ability to act as a strong proton acceptor due to the presence of multiple basic nitrogen atoms in its structure. This compound features a naphthalene backbone with two dimethylamino groups, which significantly enhance its basicity. Proton sponge is notable for its high pKa value, making it an effective agent for deprotonation reactions and a useful tool in various organic synthesis applications. It is often employed in the field of organic chemistry as a non-nucleophilic base, facilitating reactions that require the removal of protons without introducing unwanted side reactions. Additionally, proton sponge is recognized for its role in the stabilization of reactive intermediates and in the formation of stable complexes with acids. Its unique properties make it valuable in both academic research and industrial applications, particularly in the synthesis of complex organic molecules and in the development of new catalytic systems.

Formula: C₁₄H₁₈N₂

InChI: InChI=1S/C14H18N2/c1-15(2)12-9-5-7-11-8-6-10-13(14(11)12)16(3)4/h5-10H,1-4H3

InChI key: InChIKey=GJFNRSDCSTVPCJ-UHFFFAOYSA-N

SMILES: N(C)(C)C=1C=2C(N(C)C)=CC=CC2C=CC1

Synonyms:

• 1,8-Bis(Dimethylamino)Napthalene
• 1,8-Bis(N,N-dimethylamino)naphthalene
• 1,8-Bis(dimethylamino)naphtalene
• 1,8-Bis(dimethylamino)naphthalene
• 1,8-Naphthalenediamine, N,N,N',N'-tetramethyl-
• 1,8-Naphthalenediamine, N¹,N¹,N⁸,N⁸-tetramethyl-
• 1-N,1-N,8-N,8-N-Tetramethylnaphthalene-1,8-diamine
• N,N,N',N'-Tetramethyl-1,8-diaminonaphthalene
• N,N,N',N'-tetramethylnaphthalene-1,8-diamine
• N¹,N¹,N⁸,N⁸-Tetramethyl-1,8-naphthalenediamine
• Proton Sponge
• Proton-Sponge(R)
• 1,8-Naphthalenediamine, N1,N1,N8,N8-tetramethyl-

1,8-Bis(dimethylamino)naphthalene [for Dehydrohalogenation]

CAS: 20734-58-1

Formula: C₁₄H₁₈N₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 214.31

Ref: 3B-B1018

1,8-Bis(dimethylamino)naphthalene, 98+%

CAS: 20734-58-1

1,8-Bis(dimethylamino)naphthalene is used in the synthesis of C-substituted t-BuNH-8,9-R,R?-nido-7,8,9-C3B8H9 (R,R? = H,H; MeH; Me,Me; Ph,H and Ph,Ph) tricarbollide compounds. It was also used in the preparation of saturated fluoroalkyl(hydrido) complexes of Iridium. This Thermo Scientific Chemical

Formula: C₁₄H₁₈N₂

Purity: 98+%

Color and Shape: Crystalline powder, White to cream to yellow to pink or pink-brown

Molecular weight: 214.31

Ref: 02-L00313

1,8-Naphthalenediamine, N1,N1,N8,N8-tetramethyl-

CAS: 20734-58-1

Formula: C₁₄H₁₈N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 214.3061

Ref: IN-DA002IZU

1,8-Bis(dimethylamino)naphthalene

CAS: 20734-58-1

1,8-Bis(dimethylamino)naphthalene

Formula: C₁₄H₁₈N₂

Purity: 98%

Color and Shape: faint orange to faint brown solid

Molecular weight: 214.31g/mol

Ref: 54-OR21927

N,N,N',N'-Tetramethyl-1,8-naphthalene diamine

CAS: 20734-58-1

N,N,N',N'-Tetramethyl-1,8-naphthalene diamine is a protonated diamine that has been shown to be cytotoxic in vitro. It has been found to bind with high affinity to intracellular targets and transfer reactions. N,N,N',N'-Tetramethyl-1,8-naphthalene diamine is also able to induce oxidative stress in the cell. This chemical compound also has a synergic effect with other drugs and can be used as an adjuvant therapy for autoimmune diseases such as systemic lupus erythematosus (SLE). The nitrogen atoms in this compound are not bound to hydrogen atoms and have a high chemical stability.

Formula: C₁₄H₁₈N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 214.31 g/mol

Ref: 3D-FT09337

N1,N1,N8,N8-Tetramethylnaphthalene-1,8-diamine

CAS: 20734-58-1

Formula: C₁₄H₁₈N₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 214.312

Ref: 10-F210885

1,8-Bis(dimethylamino) Naphthalene (DMAN) extrapure, 99%

CAS: 20734-58-1

Formula: C₁₄H₁₈N₂

Purity: min. 99%

Color and Shape: White to yellow, Powder, Clear, Colourless to yellow

Molecular weight: 214.31

Ref: SR-98932

1,8-Bis(dimethylamino)naphthalene

Controlled Product

CAS: 20734-58-1

Applications 1,8-Bis(dimethylamino)naphthalene, also referred to as proton sponge, is a lipophilic proton trapping agent. 1,8-Bis(dimethylamino)naphthalene is used in the matrix for mass spectroscopy analysis of lipids and fatty acids.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Daniell, H. et al.: Biochem. Biophys. Res. Comm., 107, 1191 (1982); Shroff, R. et al.: Anal. Chem., 81, 7954 (2009);

Formula: C₁₄H₁₈N₂

Color and Shape: Neat

Molecular weight: 214.31

Ref: TR-B429760