CAS 20736-08-7

Saikosaponin C

Description:

Saikosaponin C is a triterpenoid saponin primarily derived from the roots of the plant Bupleurum falcatum, commonly known for its use in traditional medicine. This compound is characterized by its complex structure, which includes a steroid-like backbone and sugar moieties, contributing to its biological activity. Saikosaponin C exhibits a range of pharmacological properties, including anti-inflammatory, hepatoprotective, and immunomodulatory effects. It has been studied for its potential in treating various conditions, such as liver diseases and certain cancers. The compound is typically soluble in organic solvents and shows limited solubility in water, which is a common trait among saponins. Its mechanism of action often involves modulation of signaling pathways and interaction with cell membranes. Due to its bioactive nature, Saikosaponin C is of interest in both pharmacological research and potential therapeutic applications, although further studies are needed to fully elucidate its effects and safety profile in humans.

Formula: C₄₈H₇₈O₁₇

InChI: InChI=1S/C48H78O17/c1-22-30(51)32(53)36(57)40(61-22)65-38-24(20-59-39-35(56)33(54)31(52)23(19-49)62-39)63-41(37(58)34(38)55)64-29-11-12-44(6)25(43(29,4)5)9-13-45(7)26(44)10-14-48-27-17-42(2,3)15-16-47(27,21-60-48)28(50)18-46(45,48)8/h10,14,22-41,49-58H,9,11-13,15-21H2,1-8H3/t22-,23+,24+,25-,26+,27?,28-,29-,30-,31+,32+,33-,34+,35+,36+,37+,38+,39+,40-,41-,44-,45+,46-,47+,48-/m0/s1

InChI key: InChIKey=VJEMOEYSQDKAQF-VNPZMJFTSA-N

SMILES: C[C@]12[C@@]3(C4([C@@](CO3)([C@@H](O)C1)CCC(C)(C)C4)[H])C=C[C@]5([C@@]2(C)CC[C@@]6([C@]5(C)CC[C@H](O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O[C@H]9[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O9)[C@H](O)[C@H]7O)C6(C)C)[H])[H]

Synonyms:

• (3beta,13alpha,16beta,17alpha)-16-hydroxy-13,28-epoxyolean-11-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->4)-[beta-D-glucopyranosyl-(1->6)]-beta-D-glucopyranoside
• (3beta,4alpha,16beta)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-4)-O-beta-D-glucopyranosyl-(1-6)-beta-D-glucopyranoside
• (3β,16β)-13,28-Epoxy-16-hydroxyolean-11-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→4)-O-[β-<smallcap>D</smallcap>-glucopyranosyl-(1→6)]-β-<smallcap>D</span>-glucopyranoside
• Oleanane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,16β)-13,28-epoxy-16-hydroxyolean-11-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→4)-O-[β-<smallcap>D</span>-glucopyranosyl-(1→6)]-
• β-D-Glucopyranoside, (3β,16β)-13,28-epoxy-16-hydroxyolean-11-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-[β-D-glucopyranosyl-(1→6)]-
• Oleanane, β-D-glucopyranoside deriv.
• Cyclosaponin C
• Saikosaponin C
• (3β,16β)-13,28-Epoxy-16-hydroxyolean-11-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside

β-D-Glucopyranoside, (3β,16β)-13,28-epoxy-16-hydroxyolean-11-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-[β-D-glucopyranosyl-(1→6)]-

CAS: 20736-08-7

Formula: C₄₈H₇₈O₁₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 927.1227

Ref: IN-DA002J0P

Saikosaponin C

CAS: 20736-08-7

Formula: C₄₈H₇₈O₁₈

Molecular weight: 943.12

Ref: 7W-GP4626

Saikosaponin C

CAS: 20736-08-7

Saikosaponin C

Purity: 98%

Molecular weight: 927.12g/mol

Ref: 54-OR1023138

Saikosaponin C

CAS: 20736-08-7

Saikosaponin C

Purity: ≥98%

Molecular weight: 927.12g/mol

Ref: 54-BUP00779

Saikosaponin C

CAS: 20736-08-7

Formula: C₄₈H₇₈O₁₇

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 927.14

Ref: 3B-A3189

Saikosaponin C

CAS: 20736-08-7

Saikosaponin C (SSC) is one of the saikosaponins that are consisted in a Chinese herb, Radix Bupleuri, it yields a potent effect on inducing human umbilical vein endothelial cells (HUVECs) viability and growth, also induces endothelial cells migration and capillary tube formation.

Formula: C₄₈H₇₈O₁₇

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 927.135

Ref: BP-BP1241

Saikosaponin C

CAS: 20736-08-7

Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.

Formula: C₄₈H₇₈O₁₇

Purity: 97.27% - 99.94%

Color and Shape: Solid

Molecular weight: 927.12

Ref: TM-T3914

Saikosaponin c

CAS: 20736-08-7

Natural glycoside

Formula: C₄₈H₇₈O₁₇

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 927.14

Ref: 5G-89780

Saikosaponin C

CAS: 20736-08-7

Saikosaponin C is a triterpene saponin, which is a bioactive compound found in various medicinal plants, particularly those in the genus Bupleurum, often used in traditional Chinese medicine. It is derived from the roots of these plants, where it coexists with other saponins, contributing to their medicinal properties.

Formula: C₄₈H₇₈O₁₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 927.12 g/mol

Ref: 3D-OS45923

Saikosaponin C

CAS: 20736-08-7

Applications Saikosaponin C is an inhibitor of liposaccharide-induced apoptosis through suppression of caspase-3 activation. Neuroprotective agent.
References Li, Z. et al.: J. Ethnopharmacol., 148, 794 (2013); Lee, T. et al.: Biochem. Biophys. Res. Comm., 445, 615 (2014);

Formula: C₄₈H₇₈O₁₇

Color and Shape: White Powder

Molecular weight: 927.12

Ref: TR-S083910