CAS 207390-14-5: (1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one

Description: (1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, with CAS number 207390-14-5, is a complex organic compound characterized by its unique bicyclic structure that incorporates both a pyridine and diazocine moiety. This compound features a bromine substituent at the 9-position, which can influence its reactivity and biological activity. The stereochemistry indicated by the (1R,5S) configuration suggests specific spatial arrangements of atoms that can affect the compound's interactions with biological targets. Typically, such compounds may exhibit interesting pharmacological properties, making them of interest in medicinal chemistry. The presence of the methano bridge contributes to the rigidity of the structure, potentially impacting its conformational dynamics. Additionally, the compound's solubility, stability, and reactivity can vary based on the functional groups present and the overall molecular architecture. Understanding these characteristics is crucial for applications in drug development and synthesis.

Formula: C₁₁H₁₃BrN₂O

InChI: InChI=1S/C11H13BrN2O/c12-9-1-2-10-8-3-7(4-13-5-8)6-14(10)11(9)15/h1-2,7-8,13H,3-6H2/t7-,8+/m0/s1

InChI key: InChIKey=DWDCLEHDNICBMI-JGVFFNPUSA-N

SMILES: O=C1C(Br)=CC=C2N1CC3CNCC2C3

Synonyms:

• 3-Bromocytisine
• 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 9-bromo-1,2,3,4,5,6-hexahydro-, (1R,5S)-
• (-)-3-Bromocytisine
• 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 9-bromo-1,2,3,4,5,6-hexahydro-, (1R-cis)-
• (1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one

3-Bromocytisine

CAS: 207390-14-5

• Purity: ≥98%
• Molecular weight: 269.14g/mol

3-Bromocytisine

CAS: 207390-14-5

3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for …

• Formula: C₁₁H₁₃BrN₂O
• Purity: 98.14%
• Color and Shape: Solid
• Molecular weight: 269.14

3-Bromocytisine

CAS: 207390-14-5

3-Bromocytisine is a potent acetylcholine esterase inhibitor. It has been shown to protect against dopaminergic …

• Formula: C₄H₄BrN₃O
• Purity: Min. 95%
• Molecular weight: 190 g/mol