CAS 207390-14-5

(1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one

Description:

(1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, with CAS number 207390-14-5, is a complex organic compound characterized by its unique bicyclic structure that incorporates both a pyridine and diazocine moiety. This compound features a bromine substituent at the 9-position, which can influence its reactivity and biological activity. The stereochemistry indicated by the (1R,5S) configuration suggests specific spatial arrangements of atoms that can affect the compound's interactions with biological targets. Typically, such compounds may exhibit interesting pharmacological properties, making them of interest in medicinal chemistry. The presence of the methano bridge contributes to the rigidity of the structure, potentially impacting its conformational dynamics. Additionally, the compound's solubility, stability, and reactivity can vary based on the functional groups present and the overall molecular architecture. Understanding these characteristics is crucial for applications in drug development and synthesis.

Formula: C₁₁H₁₃BrN₂O

InChI: InChI=1S/C11H13BrN2O/c12-9-1-2-10-8-3-7(4-13-5-8)6-14(10)11(9)15/h1-2,7-8,13H,3-6H2/t7-,8+/m0/s1

InChI key: InChIKey=DWDCLEHDNICBMI-JGVFFNPUSA-N

SMILES: O=C1N2C([C@@]3(C[C@](C2)(CNC3)[H])[H])=CC=C1Br

Synonyms:

• 3-Bromocytisine
• 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 9-bromo-1,2,3,4,5,6-hexahydro-, (1R,5S)-
• (-)-3-Bromocytisine
• 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 9-bromo-1,2,3,4,5,6-hexahydro-, (1R-cis)-
• (1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one

3-Bromocytisine

CAS: 207390-14-5

3-Bromocytisine

Purity: ≥98%

Molecular weight: 269.14g/mol

Ref: 54-BUP08221

3-Bromocytisine

CAS: 207390-14-5

3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).

Formula: C₁₁H₁₃BrN₂O

Purity: 99.974%

Color and Shape: Solid

Molecular weight: 269.14

Ref: TM-T10108