CAS 207557-35-5

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile

Description:

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile is a chemical compound characterized by its unique structural features, which include a pyrrolidine ring, a chloroacetyl group, and a carbonitrile functional group. The presence of the chloroacetyl moiety introduces a polar functional group that can influence the compound's reactivity and solubility in various solvents. The carbonitrile group contributes to the compound's potential as a nucleophile or electrophile in chemical reactions. This compound is typically used in pharmaceutical research and development due to its potential biological activity, particularly in the context of drug design. The stereochemistry indicated by the "(S)" prefix suggests that the compound has a specific three-dimensional arrangement, which can significantly affect its biological interactions and pharmacological properties. Overall, (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile is a versatile compound with applications in medicinal chemistry, and its properties are influenced by the interplay of its functional groups and stereochemistry.

Formula: C₇H₉ClN₂O

InChI: InChI=1/C7H9ClN2O/c8-4-7(11)10-3-1-2-6(10)5-9/h6H,1-4H2/t6-/m0/s1

InChI key: InChIKey=YCWRPKBYQZOLCD-LURJTMIESA-N

SMILES: C(CCl)(=O)N1[C@H](C#N)CCC1

Synonyms:

• (2S)-1-(2-chloroacetyl)-2-Pyrrolidinecarbonitrile
• (2S)-1-(chloroacetyl)pyrrolidine-2-carbonitrile
• (2S)-1-chloroacetylpyrrolidine-2-carbonitrile
• (2S)-N-(Chloroacetyl)-2-Pyrrolidine Carbonitrile
• (2S)-N-Chloroacetyl-2-cyanopyrrolidine
• (S)-1-(2-Chloro-acetyl)-pyrrolidine-2-carbonitrile
• (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
• (S)-1-(Chloroacetyl)pyrrolidine-2-carbonitrile
• (S)-2-Cyanopyroolidin-1-carbonyl chloride
• (S)-2-cyanopyrrolidine-1-carbonyl chloride
• 1-(2-Chloroacetyl)-(2S)-pyrrolidine carbonitrile
• 1-Boc-4-(P-Toluenesulfonyloxymethyl)Piperidine
• 1-Chloroacetyl-2-(S)-cyanopyrrolidine
• 2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2S)-
• 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2S)-
• Vildagliptin Intermediate-1
• Vildagliptin-N1
• Vildagliptin interMediates
• 1-(2-Chloroacetyl)-pyrrolidine-(2S)-carbonitrile
• vildagliptin Impurity J
• Vildagliptin interMediate C
• Vigliptin Impurity 14
• 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2S)- (9CI)
• cas:207557-35-5
• (2S) -N-chloroacetyl-2-cyano-tetrahydropyrrole
• 2S-1-(2-Chloroacetyl)-2-9-pyrrolidinec
• (R)-hexahydroindolizin-7(1H)-one
• -2-pyrrolidinecarbonitrile
• Vogliptin impurity II
• Vildagliptin Impurity 16/Vildagliptin Chloroacetyl Nitrile (S)-Isomer/(2S)-1-(Chloroacetyl)-2-Pyrrolidinecarbonitrile
• (Vildagliptin)
• (S)-2-cyanopyrrolidine-1-carbonyl chlo
• (S)-1-(Chloroacetyl)-2-cyanopyrrolidine
• (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile
• Vildagliptin Intermediate 2
• Vildagliptin Chloroacetyl Nitrile Impurity
• (S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
• (2S)-1-chloroacetyl-2-pyrrolidine carbonitrile CAS No.
• Vildagliptin Chloroacetyl Nitrile (S)-Isomer
• Vildagliptin Impurity，(2S)-1-(Chloroacetyl)-2- pyrrolidinecarbonitrile
• (2S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile
• (2S)-1-(CHLOROACETYL)-2-PYRROLIDINECARBONITRILE
• (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile ISO 9001：2015 REACH
• (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile
• (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2S)-

CAS: 207557-35-5

Formula: C₇H₉ClN₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 172.6122

Ref: IN-DA002J4N

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile

CAS: 207557-35-5

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile

Purity: 95%

Molecular weight: 172.61g/mol

Ref: 54-OR346401

Vildagliptin Impurity 14

CAS: 207557-35-5

Formula: C₇H₉ClN₂O

Color and Shape: Off-White Solid

Molecular weight: 172.61

Ref: 4Z-V-2221

(S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

CAS: 207557-35-5

Formula: C₇H₉ClN₂O

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 172.61

Ref: 3B-C3202

(2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile

Controlled Product

CAS: 207557-35-5

Stability Hygroscopic
Applications (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile is a key intermediate for dipeptidyl peptidase IV inhibitor Vildagliptin (V305000).
References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008);

Formula: C₇H₉ClN₂O

Color and Shape: Neat

Molecular weight: 172.61

Ref: TR-C363780

Vildagliptin Chloroacetyl Nitrile (S)-Isomer

CAS: 207557-35-5

Formula: C₇H₉ClN₂O

Molecular weight: 172.61

Ref: ST-EA-CP-V1004

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile

CAS: 207557-35-5

Intermediate in the synthesis of anagliptin

Formula: C₇H₉ClN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 172.61 g/mol

Ref: 3D-FC11383

(S)-1-(2-Chloroacetyl)-pyrrolidine-2-carbonitrile

CAS: 207557-35-5

Formula: C₇H₉ClN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 172.61

Ref: 10-F049063

(2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile-d1

Controlled Product

CAS: 207557-35-5

Applications (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile-d1 is the deuterated form of (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile (C363780), which is a key intermediate for dipeptidyl peptidase IV inhibitor Vildagliptin (V305000).
References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008);

Formula: C₇DH₈ClN₂O

Color and Shape: Neat

Molecular weight: 173.618

Ref: TR-C363782

(S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile-2,5,5-d3

Controlled Product

CAS: 207557-35-5

Formula: C₇H₆D₃ClN₂O

Color and Shape: Neat

Molecular weight: 175.631

Ref: TR-C363783