CAS 207679-81-0: 5-Hydroxymethyltolterodine

Description: 5-Hydroxymethyltolterodine is a chemical compound that serves as a metabolite of tolterodine, which is primarily used in the treatment of overactive bladder. This substance is characterized by its structural features, including a hydroxymethyl group and a tolterodine backbone, which contribute to its pharmacological properties. It is typically classified as an antimuscarinic agent, functioning by inhibiting the action of acetylcholine on muscarinic receptors in the bladder, thereby reducing involuntary contractions. The compound is soluble in organic solvents and exhibits moderate stability under standard conditions. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are influenced by its chemical structure, which affects its interaction with biological systems. Research into 5-Hydroxymethyltolterodine has provided insights into its efficacy and safety profile, making it a subject of interest in pharmacological studies related to urinary disorders. As with many pharmaceuticals, understanding its characteristics is crucial for optimizing therapeutic applications and minimizing potential side effects.

Formula: C₂₂H₃₁NO₂

InChI: InChI=1S/C22H31NO2/c1-16(2)23(17(3)4)13-12-20(19-8-6-5-7-9-19)21-14-18(15-24)10-11-22(21)25/h5-11,14,16-17,20,24-25H,12-13,15H2,1-4H3/t20-/m1/s1

InChI key: InChIKey=DUXZAXCGJSBGDW-HXUWFJFHSA-N

SMILES: OC1=CC=C(C=C1C(C=2C=CC=CC2)CCN(C(C)C)C(C)C)CO

Synonyms:

• (+)-N,N-Diisopropyl-3-(2-hydroxy-5-hydroxymethylphenyl)-3-phenylpropylamine
• (R)-5-Hydroxymethyl tolterodine
• 2-[(1R)-3-[Di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenol
• 3-[(1R)-3-[Bis(1-Methylethyl)Amino]-1-Phenylpropyl]-4-Hydroxy-Benzenemethanol
• 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol
• 5-Hydroxymethyltolterodine
• Benzenemethanol, 3-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-
• Desfesoterodine
• Pnu 200577
• R-(+)-2(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethylphenol
• Spm 7605

Benzenemethanol, 3-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-

CAS: 207679-81-0

• Formula: C₂₂H₃₁NO₂
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 341.487

Desfesoterodine

CAS: 207679-81-0

Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.

• Formula: C₂₂H₃₁NO₂
• Purity: 100%
• Color and Shape: Solid
• Molecular weight: 341.49

(R)-5-Hydroxymethyl Tolterodine

CAS: 207679-81-0

Applications A metabolite of Tolterodine (T535800), a muscarinic receptor antagonist used in the treatment of …

• Formula: C₂₂H₃₁NO₂
• Color and Shape: Neat
• Molecular weight: 341.49

(R)-5-Hydroxymethyl tolterodine

CAS: 207679-81-0

(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the …

• Formula: C₂₂H₃₁NO₂
• Purity: Min. 98 Area-%
• Color and Shape: Off-White Powder
• Molecular weight: 341.49 g/mol