CAS 20780-74-9

7-Bromoisatin

Description:

7-Bromoisatin is a chemical compound that belongs to the class of isatin derivatives, characterized by the presence of a bromine atom at the 7-position of the isatin structure. Its molecular formula is C8H5BrN2O2, indicating the presence of a bromine atom, carbon, hydrogen, nitrogen, and oxygen. This compound typically appears as a solid and is known for its potential biological activities, including antimicrobial and anticancer properties. The presence of the bromine substituent can influence its reactivity and solubility, making it of interest in medicinal chemistry and organic synthesis. 7-Bromoisatin can undergo various chemical reactions, such as nucleophilic substitutions and cyclizations, which can be utilized to synthesize more complex molecules. Additionally, its structure allows for interactions with biological targets, making it a subject of research in drug development. As with many halogenated compounds, safety precautions should be taken when handling 7-Bromoisatin due to its potential toxicity and environmental impact.

Formula: C₈H₄BrNO₂

InChI: InChI=1S/C8H4BrNO2/c9-5-3-1-2-4-6(5)10-8(12)7(4)11/h1-3H,(H,10,11,12)

InChI key: InChIKey=OCVKSIWBTJCXPV-UHFFFAOYSA-N

SMILES: O=C1C=2C(=C(Br)C=CC2)NC1=O

Synonyms:

• 1H-Indole-2,3-dione, 7-bromo-
• 7-Bromo-2,3-dioxoindoline
• 7-Bromoindole-1H-2,3-dione
• 7-Bromoindole-2,3-dione
• 7-Bromoindoline-2,3-Dione
• 7-bromo-1H-indole-2,3-dione
• Indole-2,3-dione, 7-bromo-
• Isatin, 7-bromo-
• 7-Bromoisatin

7-Bromoisatin

CAS: 20780-74-9

Formula: C₈H₄BrNO₂

Purity: >97.0%(GC)

Color and Shape: Orange to Amber to Dark red powder to crystal

Molecular weight: 226.03

Ref: 3B-B3974

7-Bromoisatin, 97%

CAS: 20780-74-9

7-bromoisatin was treated with excess PhMgBr to afford tertiary alcohol 9 in 96 % yield. Isatin oxime triflates undergo a facile fragmentation which is promoted by DBU, to form anthranilonitriles after hydrolytic work-up.This Thermo Scientific Chemicals brand product was originally part of the Alfa

Formula: C₈H₄BrNO₂

Purity: 97%

Color and Shape: Red, Crystals or powder or crystalline powder

Molecular weight: 226.03

Ref: 02-H32843

1H-Indole-2,3-dione, 7-bromo-

CAS: 20780-74-9

Formula: C₈H₄BrNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 226.0269

Ref: IN-DA002JAR

7-Bromoisatin

CAS: 20780-74-9

7-Bromoisatin

Formula: C₈H₄BrNO₂

Purity: 95%

Color and Shape: red solid

Molecular weight: 226.03g/mol

Ref: 54-OR14358

7-Bromoisatin

CAS: 20780-74-9

Formula: C₈H₄BrNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 226.029

Ref: 10-F040728

7-Bromo-2,3-dioxoindoline

CAS: 20780-74-9

7-Bromo-2,3-dioxoindoline is a synthetic compound with a vibrational frequency of 249.2 cm−1. It is an inhibitor of the enzyme synthetase and has been shown to have an inhibitory effect on cancer cell viability in vitro. 7-Bromo-2,3-dioxoindoline inhibits the production of cancerous cells by interfering with their ability to synthesize DNA, which is necessary for cell division. This inhibition may be due to its ability to form intermolecular hydrogen bonding interactions with the amine group on the enzyme synthetase. 7-Bromo-2,3-dioxoindoline has also been shown to block the synthesis of 5-chloroisatin, one of its reaction products. The bioassay was carried out by measuring the amount of granulosa cells that were able to produce estrogen after treatment with this compound.

Formula: C₈H₄BrNO₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 226.03 g/mol

Ref: 3D-FB35949