CAS 20780-75-0

4-Iodoisatin

Description:

4-Iodoisatin is a chemical compound that belongs to the class of isatins, which are derived from indole and characterized by a diketopiperazine structure. It features an iodine atom substituted at the 4-position of the isatin ring, which contributes to its unique reactivity and properties. The compound typically appears as a solid and is known for its potential biological activities, including antimicrobial and anticancer properties. 4-Iodoisatin can participate in various chemical reactions, such as nucleophilic substitutions and cyclizations, making it a valuable intermediate in organic synthesis. Its solubility can vary depending on the solvent, and it is often used in research settings to explore its pharmacological effects and as a building block for more complex molecules. Additionally, the presence of the iodine atom can enhance the compound's lipophilicity, influencing its interaction with biological systems. Overall, 4-Iodoisatin is a significant compound in medicinal chemistry and synthetic organic chemistry due to its diverse applications and interesting chemical behavior.

Formula: C₈H₄INO₂

InChI: InChI=1S/C8H4INO2/c9-4-2-1-3-5-6(4)7(11)8(12)10-5/h1-3H,(H,10,11,12)

InChI key: InChIKey=NYWOXCHAPWQNFC-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC1=O)=CC=CC2I

Synonyms:

• 1H-Indole-2,3-dione, 4-iodo-
• 4-Iodo-1H-indole-2,3-dione
• 4-Iodoisatin
• Indole-2,3-dione, 4-iodo-
• Isatin, 4-iodo-

1H-Indole-2,3-dione, 4-iodo-

CAS: 20780-75-0

Formula: C₈H₄INO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 273.0273

Ref: IN-DA002JAQ

4-Iodoindoline-2,3-dione

CAS: 20780-75-0

4-Iodoindoline-2,3-dione

Formula: C₈H₄INO₂

Purity: ≥95%

Color and Shape: very dark orange powder

Molecular weight: 273.03g/mol

Ref: 54-OR471590

4-Iodoisatin

CAS: 20780-75-0

4-Iodoisatin is a heterocyclic compound that can be synthesized by cross-coupling reactions. It has been shown to inhibit the production of prostaglandin E2, COX-2 protein, and tumor necrosis factor in mouse macrophages. 4-Iodoisatin also inhibits the production of protein kinase C (PKC) in these cells. 4-Iodoisatin can be modified into a dimer form with many different substitutions on the ring structure and this modification increases its potency as an inhibitor of PKC. Irradiation can decompose the compound into a single isomer that is more potent than either of the two isomers. This drug may have therapeutic potential for treatment of cancer, arthritis, and other inflammatory disorders.

Formula: C₈H₄INO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 273.03 g/mol

Ref: 3D-FI67680

4-Iodoindoline-2,3-dione

CAS: 20780-75-0

Formula: C₈H₄INO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 273.029

Ref: 10-F091652