CAS 20782-91-6

2-(bromomethyl)-5-nitrofuran

Description:

2-(Bromomethyl)-5-nitrofuran is a chemical compound characterized by its furan ring structure, which is a five-membered aromatic heterocycle containing one oxygen atom. The presence of a bromomethyl group (-CH2Br) at the 2-position and a nitro group (-NO2) at the 5-position contributes to its reactivity and potential applications in organic synthesis. This compound is typically a yellow to brown solid and is soluble in organic solvents. The bromomethyl group can serve as a versatile electrophile in nucleophilic substitution reactions, while the nitro group can participate in various chemical transformations, including reduction and electrophilic aromatic substitution. Due to its functional groups, 2-(bromomethyl)-5-nitrofuran may exhibit biological activity, making it of interest in medicinal chemistry and material science. Safety precautions should be taken when handling this compound, as both brominated and nitro compounds can pose health risks. Proper storage and disposal methods are essential to mitigate any environmental impact.

Formula: C₅H₄BrNO₃

InChI: InChI=1/C5H4BrNO3/c6-3-4-1-2-5(10-4)7(8)9/h1-2H,3H2

SMILES: c1cc(N(=O)=O)oc1CBr

Synonyms:

• 5-Nitro-2-furfuryl bromide

Furan, 2-(bromomethyl)-5-nitro-

CAS: 20782-91-6

Formula: C₅H₄BrNO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 205.9942

Ref: IN-DA002JBD

2-(Bromomethyl)-5-Nitrofuran

CAS: 20782-91-6

2-(Bromomethyl)-5-Nitrofuran

Purity: 95%

Molecular weight: 205.99g/mol

Ref: 54-OR1027264

2-(Bromomethyl)-5-nitrofuran

CAS: 20782-91-6

2-(Bromomethyl)-5-nitrofuran is a hydroxyl-containing molecule that is able to target hypoxic tumor sites. It has been shown to be effective against ges-1 cells, which are the most common cell type in the bone marrow and are resistant to chemotherapy. 2-(Bromomethyl)-5-nitrofuran causes DNA damage by reacting with amines, such as methylamine, and nucleophilic groups, such as thiols. This molecule also has antibacterial properties, which may be due to its ability to react with bacterial cytochrome P450 enzymes. 2-(Bromomethyl)-5-nitrofuran can be synthesized from commercially available starting materials in an economically feasible manner.

Formula: C₅H₄BrNO₃

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 205.99 g/mol

Ref: 3D-FB34549