Casein Kinase Inhibitor A86 is a chemical compound known for its role in inhibiting casein kinases, which are a group of serine/threonine kinases involved in various cellular processes, including cell cycle regulation and signal transduction. This compound is often utilized in biochemical research to study the effects of casein kinase inhibition on cellular functions and signaling pathways. A86 is characterized by its specific binding affinity to casein kinases, which allows it to effectively modulate their activity. The compound is typically used in laboratory settings, and its effects can vary depending on the concentration and the specific cellular context. As a small molecule inhibitor, A86 may also exhibit potential therapeutic applications, particularly in diseases where casein kinase activity is dysregulated. However, detailed studies are necessary to fully understand its pharmacological properties, including its bioavailability, metabolism, and potential side effects. Overall, Casein Kinase Inhibitor A86 represents a valuable tool in the field of molecular biology and pharmacology for investigating kinase-related pathways.

Casein Kinase inhibitor A86

2079069-01-3: Casein Kinase Inhibitor A86 is a chemical compound known for its role in inhibiting casein kinases, which are a group of serine/threonine kinases involved in various cellular processes, including cell cycle regulation and signal transduction. This compound is often utilized in biochemical research to study the effects of casein kinase inhibition on cellular functions and signaling pathways. A86 is characterized by its specific binding affinity to casein kinases, which allows it to effectively modulate their activity. The compound is typically used in laboratory settings, and its effects can vary depending on the concentration and the specific cellular context. As a small molecule inhibitor, A86 may also exhibit potential therapeutic applications, particularly in diseases where casein kinase activity is dysregulated. However, detailed studies are necessary to fully understand its pharmacological properties, including its bioavailability, metabolism, and potential side effects. Overall, Casein Kinase Inhibitor A86 represents a valuable tool in the field of molecular biology and pharmacology for investigating kinase-related pathways.

<p>trans-N1-(4-(5-(Cyclopropylmethyl)-1-methyl-1H-pyrazol-4-yl)-5-fluoropyrimidin-2-yl)cyclohexane-1,4-diamine</p>

trans-N1-(4-(5-(Cyclopropylmethyl)-1-methyl-1H-pyrazol-4-yl)-5-fluoropyrimidin-2-yl)cyclohexane-1,4-diamine

<p>Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α) and also inhibits CDK7 (TFIIH) and CDK9 (P-TEFb). It induces apoptosis in leukemia cells, exhibiting substantial anti-leukemic effects.</p>

CAS 2079069-01-3

Casein Kinase inhibitor A86

trans-N1-(4-(5-(Cyclopropylmethyl)-1-methyl-1H-pyrazol-4-yl)-5-fluoropyrimidin-2-yl)cyclohexane-1,4-diamine

Ref: 54-PC1003887

Casein Kinase inhibitor A86

Ref: TM-T39482