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CAS 207919-09-3

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2,3,4-trifluorobenzamide

Description:
2,3,4-Trifluorobenzamide is an aromatic compound characterized by the presence of a benzene ring substituted with three fluorine atoms and an amide functional group. The fluorine atoms are located at the 2, 3, and 4 positions of the benzene ring, which significantly influences the compound's chemical properties, including its reactivity and polarity. The amide group (-CONH2) contributes to the compound's ability to engage in hydrogen bonding, affecting its solubility in polar solvents. This compound is typically a solid at room temperature and may exhibit moderate stability under standard conditions. Its fluorinated structure can enhance lipophilicity and alter biological activity, making it of interest in pharmaceutical and agrochemical research. Additionally, the presence of fluorine can improve metabolic stability and bioavailability in drug design. Safety data should be consulted for handling and potential toxicity, as fluorinated compounds can exhibit unique environmental and health effects.
Formula:C7H4F3NO
InChI:InChI=1/C7H4F3NO/c8-4-2-1-3(7(11)12)5(9)6(4)10/h1-2H,(H2,11,12)
SMILES:c1cc(c(c(c1C(=N)O)F)F)F
Synonyms:
  • Trifluorobenzamide1
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