CAS 2079895-42-2

CDK2-IN-4

CAS: 2079895-42-2

CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.

Formula: C₂₃H₁₈N₆O₂S

Purity: 97.24% - 99.10%

Color and Shape: Solid

Molecular weight: 442.49

Ref: TM-T14916

CDK2 inhibitor 73

CAS: 2079895-42-2

Formula: C₂₃H₁₈N₆O₂S

Purity: 98%

Molecular weight: 442.4930

Ref: IN-DA01V2O6

CDK2-IN-4

CAS: 2079895-42-2

CDK2-IN-4

Purity: ≥95%

Molecular weight: 442.49g/mol

Ref: 54-BUP04199

CDK2-IN-4

CAS: 2079895-42-2

Purity: 98%

Molecular weight: 442.121

Ref: 10-F840857

CDK2-IN-4

CAS: 2079895-42-2

CDK2-IN-4 is a synthetic small molecule that inhibits the activity of kinases. It has been shown to inhibit the activity of CDK2, CDK4, and CDK6 in leukaemia cells. CDK2-IN-4 also inhibits the activity of kinases in other cancer cell lines. The synthesis of this compound was accomplished using a cross-coupling reaction between aryl boronic acid and aniline derivatives. This synthesis was pursued through kinetic studies involving alkylation reactions with 2-(3,5-dimethylpyrazol-1-yl)pyridinium bromide (DMPP). Kinetic parameters were determined by isothermal titration calorimetry (ITC).

Formula: C₂₃H₁₈N₆O₂S

Purity: Min. 95%

Molecular weight: 442.49 g/mol

Ref: 3D-EID89542