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CAS 208111-98-2

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TV-BK (Travoprost)

Description:
Travoprost, identified by its CAS number 208111-98-2, is a synthetic prostaglandin analog primarily used in the treatment of glaucoma and ocular hypertension. It functions by increasing the outflow of aqueous humor, thereby reducing intraocular pressure. Travoprost is characterized by its potent agonistic activity at the prostaglandin FP receptor, which is crucial for its therapeutic effects. The substance is typically administered as an ophthalmic solution and is known for its efficacy in lowering eye pressure. In terms of physical properties, Travoprost is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. Its chemical structure includes a carboxylic acid group and a long hydrocarbon chain, contributing to its biological activity. Travoprost is generally well-tolerated, although some patients may experience side effects such as eye irritation or changes in iris pigmentation. Overall, Travoprost represents a significant advancement in the management of conditions associated with elevated intraocular pressure.
Formula:C25H21F3O6
InChI:InChI=1/C25H21F3O6/c26-25(27,28)16-7-4-8-18(11-16)32-14-17(29)9-10-19-20-12-23(30)33-22(20)13-21(19)34-24(31)15-5-2-1-3-6-15/h1-11,19-22H,12-14H2/b10-9+/t19-,20-,21-,22+/m1/s1
Synonyms:
  • (3aR,4R,5R,6aS)-2-oxo-4-{(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}hexahydro-2H-cyclopenta[b]furan-5-yl benzoate
  • 2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)hexahydro-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-, (3aR,4R,5R,6aS)-
  • (3aR,4R,5R,6aS)-5-(Benzoyloxy)hexahydro-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-2H-cyclopenta[b]furan-2-one
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