CAS 208538-73-2
:Micafungin Sodium
Description:
Micafungin sodium is an antifungal agent belonging to the echinocandin class, primarily used in the treatment of invasive fungal infections, particularly those caused by Candida and Aspergillus species. It functions by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the fungal cell wall, thereby compromising the structural integrity of the fungus and leading to cell lysis. Micafungin is typically administered intravenously and is characterized by its broad-spectrum activity against various fungal pathogens, making it a valuable option in clinical settings, especially for immunocompromised patients. The substance is soluble in water and exhibits stability under physiological conditions. Its pharmacokinetics involve a relatively long half-life, allowing for once-daily dosing. Common side effects may include infusion-related reactions, liver enzyme elevations, and gastrointestinal disturbances. Due to its mechanism of action and safety profile, micafungin is often preferred in cases where other antifungal therapies may be less effective or contraindicated.
InChI:InChI=1/C56H71N9O23S.Na/c1-4-5-6-17-86-32-14-11-28(12-15-32)39-21-33(63-87-39)27-7-9-29(10-8-27)49(75)58-34-20-38(70)52(78)62-54(80)45-46(72)25(2)23-65(45)56(82)43(37(69)22-41(57)71)60-53(79)44(48(74)47(73)30-13-16-36(68)40(18-30)88-89(83,84)85)61-51(77)35-19-31(67)24-64(35)55(81)42(26(3)66)59-50(34)76;/h7-16,18,21,25-26,31,34-35,37-38,42-48,52,66-70,72-74,78H,4-6,17,19-20,22-24H2,1-3H3,(H2,57,71)(H,58,75)(H,59,76)(H,60,79)(H,61,77)(H,62,80)(H,83,84,85);/q;+1/p-1/t25-,26-,31+,34?,35-,37+,38+,42-,43-,44-,45-,46-,47+,48?,52-;/m1./s1
SMILES:CCCCCOc1ccc(cc1)c1cc(c2ccc(cc2)C(=O)NC2CC(C(N=C(C3C(C(C)CN3C(=O)C(C(CC(=N)O)O)N=C(C(C(C(c3ccc(c(c3)OS(=O)(=O)O)O)O)O)N=C(C3CC(CN3C(=O)C(C(C)O)N=C2O)O)O)O)O)O)O)O)no1.[Na]
Synonyms:- Fk 463
- 5-((1S,2S)-2-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-20-((1R)-3-Amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((1R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxo-9-((4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzoyl)amino)tetracosahydro-1H-dipyrrolo(2,1-c:2',1'-l)(1,4,7,10,13,16)hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl sodium sulfate
- Fk463
- Unii-Is1Up79R56
- Pneumocandin A0, 1-((4R,5R)-4,5-dihydroxy-N2-(4-(5-(5-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxy-3-(sulfooxy)phenyl)-L-threonine)-, monosodium salt
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Found 12 products.
Micafungin Sodium
CAS:Formula:C56H70N9O23SNaPurity:≥97% (HPLC)Color and Shape:white to beige powderMolecular weight:1292.26Micafungin Sodium (INTERNATIONAL COLD SHIPMENT REQUIRED)
CAS:<p>Antibiotics nesoi</p>Formula:C56H70N9NaO23SColor and Shape:White PowderMolecular weight:1291.4203Pneumocandin A0, 1-[(4R,5R)-4,5-dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-, sodium salt (1:1)
CAS:Formula:C56H70N9NaO23SPurity:97%Color and Shape:SolidMolecular weight:1292.2563Micafungin Sodium Salt
CAS:Formula:C56H70N9O23S·NaColor and Shape:White To Off-White Solid SolidMolecular weight:1269.29 22.99Micafungin sodium
CAS:Formula:C56H71N9O23S·NaPurity:≥ 98.0% (anhydrous)Color and Shape:White to off-white or beige powderMolecular weight:1292.28Micafungin sodium
CAS:<p>Micafungin sodium (FK 463) is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri</p>Formula:C56H70N9NaO23SPurity:98% - 99.41%Color and Shape:SolidMolecular weight:1292.26Micafungin Sodium
CAS:<p>Stability Hygroscopic<br>Applications An echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections.<br>References Chen, S.C. et al.: Drugs, 71, 11 (2011); Groll, A.H. et al.: Opin. Anti-Infect. Invest. Drugs, 2, 405 (2000); Tomishima, M. et al.: J. Antibiot., 52, 674 (1999);<br></p>Formula:C56H70N9O23S·NaColor and Shape:Off WhiteMolecular weight:1292.26Micafungin sodium - Bio-X ™
CAS:<p>Micafungin, as one of three echinocandina, has been proven to be a successful antifungal therapeutic in treating general Candida fungus infections. The treatment of immunocompromised patients is particularly important as Candida infections cause high mortality rates in patients in intensive care units, receiving chemotherapy, or stem cell transplants. This product acts as an anti-fungal by inhibiting the 1,3-beta-D-glucan synthase enzyme. As a result the production of 1,3-beta-D-glucan, which is crucial to the fungal cell wall, is hindered. Thus, the fungal cell wall loses integrity allowing for osmotic instability and cell lysis to occur.</p>Formula:C56H71N9O23S•NaPurity:Min. 95%Color and Shape:PowderMolecular weight:1,293.27 g/molMicafungin sodium
CAS:<p>Anti-fungal; glucan synthase inhibitor</p>Formula:C56H70N9NaO23SPurity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:1,292.26 g/molMicafungin-¹³C₆ Sodium
CAS:Controlled ProductFormula:C50C6H70N9NaO23SColor and Shape:NeatMolecular weight:1298.22Micafungin-d11 Sodium
CAS:Controlled Product<p>Applications Micafungin-d11 Sodium is the isotope labelled analog of Micafungin Sodium (M342350); an echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall. Micafungin Sodium also represents a valuable treatment option for fungal infections.<br>References Chen, S.C. et al.: Drugs, 71, 11 (2011); Groll, A.H. et al.: Opin. Anti-Infect. Invest. Drugs, 2, 405 (2000); Tomishima, M. et al.: J. Antibiot., 52, 674 (1999)<br></p>Formula:C56H59D11N9NaO23SColor and Shape:NeatMolecular weight:1303.33
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