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CAS 2085843-51-0

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Found 2 products.
  • Afatinib Impurity 20

    CAS:
    Formula:C22H23ClFN5O2
    Molecular weight:443.91

    Ref: ST-EA-CP-A50032

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  • Neptinib

    CAS:
    <p>Neptinib (NEP010), a derivative of Afatinib, exhibits enhanced antitumor properties and improved pharmacokinetics when administered orally. It demonstrates a notable suppression of tumor expansion in mouse models of non-small cell lung cancer harboring various EGFR mutations. Furthermore, Neptinib effectively inhibits the EGFR kinase family, exhibiting IC 50 values of 0.24 nM for EGFR wt, 7.25 nM for EGFR L858R/T790M, 0.46 nM for EGFR L858R, and 1.79 nM for EGFR T790M.</p>
    Formula:C22H23ClFN5O2
    Color and Shape:Solid
    Molecular weight:443.90