CAS 20866-56-2

boc-L-tyrosine hydroxysuccinimide ester

Description:

Boc-L-tyrosine hydroxysuccinimide ester is a chemical compound that serves as a derivative of the amino acid tyrosine, modified to enhance its reactivity for various applications in peptide synthesis and bioconjugation. The "Boc" (tert-butyloxycarbonyl) group is a protective group commonly used in organic synthesis to shield the amino group of the amino acid, facilitating selective reactions. The hydroxysuccinimide ester moiety is known for its ability to react with primary amines, making it useful for forming stable amide bonds in peptide coupling reactions. This compound is typically utilized in the synthesis of peptides and proteins, particularly in the context of drug development and biochemistry research. Its characteristics include good solubility in organic solvents, stability under standard laboratory conditions, and the ability to undergo hydrolysis, releasing the active tyrosine residue upon reaction with amines. Overall, Boc-L-tyrosine hydroxysuccinimide ester is a valuable tool in the field of chemical biology and peptide chemistry.

Formula: C₁₈H₂₂N₂O₇

InChI: InChI=1/C18H22N2O7/c1-18(2,3)26-17(25)19-13(10-11-4-6-12(21)7-5-11)16(24)27-20-14(22)8-9-15(20)23/h4-7,13,21H,8-10H2,1-3H3,(H,19,25)

SMILES: CC(C)(C)OC(=NC(Cc1ccc(cc1)O)C(=O)ON1C(=O)CCC1=O)O

Synonyms:

• Boc-Tyr-OSu
• 2,5-dioxopyrrolidin-1-yl N-(tert-butoxycarbonyl)tyrosinate

Boc-tyr-osu

CAS: 20866-56-2

Formula: C₁₈H₂₂N₂O₇

Color and Shape: Solid

Molecular weight: 378.3765

Ref: IN-DA003OIH

Boc-Tyr-OSu

CAS: 20866-56-2

Molecular weight: 378.38

Ref: 7W-GM8658

Boc-L-tyrosine N-hydroxysuccinimide ester

CAS: 20866-56-2

Boc-L-tyrosine N-hydroxysuccinimide ester is a linker that is used for the synthesis of peptides. It has good solubility in dimethylformamide and can be incorporated into synthetic peptides. Boc-L-tyrosine N-hydroxysuccinimide ester reacts with lysine residues to form amide bonds, which are stable under physiological conditions. It also has a hydroxy group that can be used to conjugate other molecules. This linker has been used in vitro studies and clinical trials, as well as for the preparation of peptidyl conjugates for histological analysis.

Formula: C₁₈H₂₂N₂O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 378.38 g/mol

Ref: 3D-FB47823

Boc-L-tyrosine N-hydroxysuccinimide ester

CAS: 20866-56-2

Formula: C₁₈H₂₂N₂O₇

Purity: 98.0%

Color and Shape: Liquid, No data available.

Molecular weight: 378.381

Ref: 10-F492703