CAS 2088771-60-0

((R)-4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-L-aspartic acid

CAS: 2088771-60-0

((R)-4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-L-aspartic acid

Purity: 98%

Molecular weight: 523.39g/mol

Ref: 54-PC1005894

Sitagliptin Tablets EP Impurity FP-A (Mixture of Diastereomers)

CAS: 2088771-60-0

Formula: C₂₀H₁₉F₆N₅O₅

Color and Shape: White To Off-White Solid

Molecular weight: 523.39

Ref: 4Z-S-2047

(R)-Sitagliptin rac-Fumarate Adduct (mixture of diastereomers)

CAS: 2088771-60-0

Impurity Sitagliptin Tablets EP Impurity FP-A
Applications Sitagliptin Fumarate Adduct is an impurity of Sitagliptin (S491000), a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
References Kim, D., et al.: J. Med. Chem. 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005), Bergman, A., et al: Clin. Ther. 28, 55 (2006)

Formula: C₂₀H₁₉F₆N₅O₅

Color and Shape: White To Off-White

Molecular weight: 523.38

Ref: TR-S491040

Sitagliptin FP Impurity A

CAS: 2088771-60-0

Formula: C₂₀H₁₉F₆N₅O₅

Molecular weight: 523.39

Ref: ST-EA-CP-S3013

(R)-Sitagliptin rac-fumarate adduct

CAS: 2088771-60-0

(R)-Sitagliptin rac-fumarate adduct is an analytical reference material and impurity standard. It is a natural product that is synthesized using a custom synthesis with analytical data available. The impurities of the synthetic process are well defined, with the exception of (1) an unknown peak at retention time 9.7 min and (2) a peak at retention time 12.5 min that may be due to the presence of fumaric acid or its derivatives. This product can be used for drug development research and development, as well as for establishing HPLC standards for pharmacopoeia testing.

Formula: C₂₀H₁₉F₆N₅O₅

Purity: Min. 95%

Molecular weight: 523.40 g/mol

Ref: 3D-NID77160