CAS 2088771-61-1

(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione

Description:

The chemical substance known as (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione, with the CAS number 2088771-61-1, is a complex organic compound characterized by its unique structural features, including multiple heterocycles and fluorinated aromatic groups. The presence of trifluoromethyl and trifluorobenzyl substituents suggests significant lipophilicity, which may influence its biological activity and pharmacokinetic properties. The compound's tetrahydrotriazole and triazine moieties contribute to its potential as a bioactive molecule, possibly exhibiting properties relevant to medicinal chemistry. Its stereochemistry, indicated by the (R) configuration, may play a crucial role in its interaction with biological targets, affecting its efficacy and safety profile. Overall, this compound represents a class of fluorinated heterocycles that may have applications in drug discovery and development, particularly in areas requiring potent and selective agents. Further studies would be necessary to elucidate its specific properties and potential applications.

Formula: C₁₆H₁₃F₆N₅O₂

Synonyms:

• (10R)?- 6,?7,?10,?11-?Tetrahydro-?3-?(trifluoromethyl)?-?10-?[(2,?4,?5-?trifluorophenyl)?methyl]?-1,?2,?4-?triazolo[3,?4-?c]?[1,?4,?7]?triazecine-?8,?12(5H,?9H)?-?dione
• Sitagliptin impurity 6/Sitagliptin FP Impurity B/Sitagliptin Triazecine Analog/10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro [1,2,4] triazolo [3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione
• (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)
• Sitagliptin Impurity FP-B
• Sitagliptin Impurity 20
• Sitagliptin FP Impurity B/ Sitagliptin Triazecine Analog
• Sitagliptin FP Impurity B
• 1,2,4-Triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione, 6,7,10,11-tetrahydro-3-(trifluoromethyl)-10-[(2,4,5-trifluorophenyl)methyl]-, (10R)-
• (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione
• Sitagliptin-17
• Impurity FP-B

Sitagliptin (R)-Triazecine Analog ((R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione)

CAS: 2088771-61-1

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Formula: C₁₆H₁₃F₆N₅O₂

Color and Shape: Off-White Solid

Molecular weight: 421.09734

Ref: 45-1A02620

(R)-Sitagliptin Tablets EP Impurity FP-B ((R)-Sitagliptin Triazecine Analog)

CAS: 2088771-61-1

Formula: C₁₆H₁₃F₆N₅O₂

Molecular weight: 421.30

Ref: 4Z-S-20135

(10R)​- 6,​7,​10,​11-​Tetrahydro-​3-​(trifluoromethyl)​-​10-​[(2,​4,​5-​trifluorophenyl)​methyl]​-1,​2,​4-​triazolo[3,​4-​c]​[1,​4,​7]​triazecine-​8,​12(5H,​9H)​-​dione

Controlled Product

CAS: 2088771-61-1

Applications (10R)-Sitagliptin Triazecine Analog is related to the family of Sitagliptin compounds which has recently been approved for the therapy of type II diabetes.
References Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005), Bergman, A., et al: Clin. Ther. 28, 55 (2006)

Formula: C₁₆H₁₃F₆N₅O₂

Color and Shape: Off-White

Molecular weight: 421.297

Ref: TR-S493150

Sitagliptin FP Impurity B

CAS: 2088771-61-1

Formula: C₁₆H₁₃F₆N₅O₂

Molecular weight: 421.30

Ref: ST-EA-CP-S3002