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CAS 2088771-62-2

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Found 2 products.
  • Sitagliptin Impurity 95
    TLC
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    Sitagliptin Impurity 95

    CAS:
    Formula:C31H31F9N6O4
    Molecular weight:722.61

    Ref: 4Z-S-20124

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • tert-Butyl ((R)-4-Oxo-4-(((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyraz…
    TRC
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    tert-Butyl ((R)-4-Oxo-4-(((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)amino)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate

    Controlled Product
    CAS:

    Applications tert-Butyl ((R)-4-Oxo-4-(((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)amino)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate is an intermediate in the synthesis of 3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin (A633385), which is an impurity of Sitagliptin (S490990). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.
    References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006)

    Formula:C31H31F9N6O4
    Color and Shape:Neat
    Molecular weight:722.601

    Ref: TR-B208870

    500mg
    1,530.00€