
CAS 2089065-77-8
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Found 4 products.
Macitentan Sulfamide Dimer (N,N''-[1,2-Ethanediylbis[oxy[5-(4-bromophenyl)-6,4-pyrimidinediyl]]]bis[N'-propylsulfamide])
CAS:Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoiFormula:C28H32Br2N8O6S2Color and Shape:Off-White SolidMolecular weight:798.0253Macitentan Impurity 4
CAS:Formula:C28H32Br2N8O6S2Color and Shape:White To Off-White SolidMolecular weight:800.54O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan
CAS:Controlled Product<p>Applications O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan is an impurity of Macitentan (M105005); a dual orally active and potent endothelin receptor antagonist used for pulmonary arterial hypertension.<br>References Emoto, N. Ensho to Men'eki, 20, 487 (2012); Bruderer, S., et al.: Xenobiotica, 42, 901 (2012); Bolli, M.H., et al.: J. Med. Chem., 55, 7849 (2012)<br></p>Formula:C28H32Br2N8O6S2Color and Shape:NeatMolecular weight:800.54




