CAS 208993-54-8: Fiduxosin

Description: Fiduxosin is a chemical compound classified as a selective antagonist of the alpha-1 adrenergic receptor, primarily used in the treatment of benign prostatic hyperplasia (BPH). It functions by relaxing the smooth muscles in the prostate and bladder neck, thereby improving urinary flow and reducing symptoms associated with BPH. The molecular structure of fiduxosin includes a piperidine ring, which contributes to its pharmacological activity. It exhibits a favorable pharmacokinetic profile, with good oral bioavailability and a moderate half-life, allowing for once-daily dosing. Additionally, fiduxosin has been studied for its potential effects on cardiovascular parameters, although it is primarily focused on urological applications. As with many medications, potential side effects may include dizziness, fatigue, and orthostatic hypotension, particularly upon initiation of therapy. Overall, fiduxosin represents a targeted approach in managing urinary symptoms related to prostate enlargement, with ongoing research into its broader therapeutic implications.

Formula: C₃₀H₂₉N₅O₄S

InChI: InChI=1S/C30H29N5O4S/c1-38-22-10-7-11-23-24(22)20-16-34(15-19(20)17-39-23)12-5-6-13-35-29(36)27-25(33-30(35)37)26-28(40-27)31-14-21(32-26)18-8-3-2-4-9-18/h2-4,7-11,14,19-20H,5-6,12-13,15-17H2,1H3,(H,33,37)/t19-,20-/m1/s1

InChI key: InChIKey=WDTAYDBPNYFWDR-WOJBJXKFSA-N

SMILES: O=C1NC=2C=3N=C(C=NC3SC2C(=O)N1CCCCN4CC5C=6C(OC)=CC=CC6OCC5C4)C7=CC=CC=C7

Synonyms:

• 8-Phenyl-3-[4-[(3aR,9bR)-1,3a,4,9b-tetrahydro-9-methoxy[1]benzopyrano[3,4-c]pyrrol-2(3H)-yl]butyl]pyrazino[2',3':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione
• 8-Phenyl-3-[4-[(3aR,9bR)-1,3a,4,9b-tetrahydro-9-methoxy[1]benzopyrano[3,4-c]pyrrol-2(3H)-yl]butyl]pyrazino[2′,3′:4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione
• Fiduxosin
• Pyrazino[2′,3′:4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione, 8-phenyl-3-[4-[(3aR,9bR)-1,3a,4,9b-tetrahydro-9-methoxy[1]benzopyrano[3,4-c]pyrrol-2(3H)-yl]butyl]-
• pyrazino[2',3':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione, 8-phenyl-3-[4-[(3aR,9bR)-1,3a,4,9b-tetrahydro-9-methoxy[1]benzopyrano[3,4-c]pyrrol-2(3H)-yl]butyl]-

Fiduxosin

CAS: 208993-54-8

• Formula: C₃₀H₂₉N₅O₄S
• Color and Shape: Neat
• Molecular weight: 555.647

Fiduxosin-d6

CAS: 208993-54-8

• Formula: C₃₀H₂₃D₆N₅O₄S
• Color and Shape: Neat
• Molecular weight: 375.44

Fiduxosin

CAS: 208993-54-8

Fiduxosin is a peptide that belongs to the class of ligands, which are small molecules …

• Formula: C₃₀H₂₉N₅O₄S
• Purity: Min. 95%
• Molecular weight: 555.6 g/mol

Fiduxosin

CAS: 208993-54-8

Fiduxosin is a selective and potent α1-adrenoceptor antagonist with inhibitory effects on α1a-adrenoceptor, α1b-adrenoceptor and …

• Formula: C₃₀H₂₉N₅O₄S
• Purity: 99.73%
• Color and Shape: Solid
• Molecular weight: 555.65