CAS 209006-18-8

4-Chloro-L-phenylalanyl-D-cysteinyl-3-(3-pyridyl)-L-alanyl-D-tryptophyl-L-lysyl-3-(methyl)-L-valyl-L-cysteinyl-3-(2-naphthyl)-L-alaninamide cyclic (2-7) disulfide

Description:

4-Chloro-L-phenylalanyl-D-cysteinyl-3-(3-pyridyl)-L-alanyl-D-tryptophyl-L-lysyl-3-(methyl)-L-valyl-L-cysteinyl-3-(2-naphthyl)-L-alaninamide cyclic (2-7) disulfide, with CAS number 209006-18-8, is a complex synthetic peptide characterized by its cyclic structure and disulfide bond formation, which contributes to its stability and biological activity. The presence of multiple amino acid residues, including both L- and D-enantiomers, suggests potential interactions with biological systems, possibly influencing receptor binding or enzymatic activity. The incorporation of aromatic and heterocyclic groups, such as pyridine and naphthalene, may enhance lipophilicity and facilitate membrane permeability. This compound's unique sequence and structural features could make it of interest in medicinal chemistry, particularly in the development of therapeutics targeting specific biological pathways. Its synthesis and characterization would require advanced techniques in peptide chemistry, and its biological properties would need to be evaluated through rigorous pharmacological studies to determine efficacy and safety profiles.

Formula: C₅₉H₇₁ClN₁₂O₈S₂

Synonyms:

• Prl-2915
• H-P-Chloro-Phe-D-Cys-Beta-(3-Pyridyl)-Ala-D-Trp-Lys-Tbu-Gly-Cys-2-Nal-Nh2

H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH₂

CAS: 209006-18-8

PRL2915, Cpa-D-Cys-Pal-D-Trp-Lys-Tle-Cys-Nal-amide, highly potent human somatostatin subtype 2 receptor (hsst2) antagonist with a Ki of 12 nM. Ki values for the other subtypes were >1000 nM for hsst1, 100 ± 57 nM for hsst3, 895 nM for hsst4, and 520 nM for hsst5, respectively. No agonist activity was found when tested alone at concentrations up to 10 µM. In a rat pituitary growth hormone in vitro antagonist assay versus somatostatin-14 (1nM) the somatostatin octapeptide analog PRL2915 exhibited an IC₅₀ value of 1.8 nM.

Formula: C₅₉H₇₁ClN₁₂O₈S₂

Purity: > 96%

Color and Shape: White Lyophilisate

Molecular weight: 1175.87

Ref: 01-4044525

PRL 2915

CAS: 209006-18-8

PRL 2915 is a potent antagonist of the human somatostatin subtype 2 receptor (hsst 2), exhibiting a binding affinity (K_i) of 12 nM [1].

Formula: C₅₉H₇₁ClN₁₂O₈S₂

Color and Shape: Solid

Molecular weight: 1175.85

Ref: TM-T76594

H-p-Chloro-Phe-D-Cys-b-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 trifluoroacetate salt (Disulfide bond)

CAS: 209006-18-8

Please enquire for more information about H-p-Chloro-Phe-D-Cys-b-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 trifluoroacetate salt (Disulfide bond) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₅₉H₇₁ClN₁₂O₈S₂

Purity: Min. 95%

Molecular weight: 1,175.86 g/mol

Ref: 3D-FC109706