YM-60828, also known as MsOH salt, is a chemical compound that belongs to a class of substances known for their potential therapeutic applications, particularly in the field of medicinal chemistry. It is characterized by its unique molecular structure, which includes specific functional groups that contribute to its biological activity. The compound is typically studied for its effects on various biological pathways, and it may exhibit properties such as anti-inflammatory or analgesic effects, depending on its mechanism of action. YM-60828 is often evaluated in preclinical studies to assess its pharmacokinetics, efficacy, and safety profile. As with many compounds in drug development, its solubility, stability, and interaction with biological targets are critical factors that influence its potential as a therapeutic agent. Researchers continue to explore its applications and optimize its properties for better performance in clinical settings.

YM-75466 is a factor Xa inhibitor potentially for the treatment of thrombosis.  YM-75466 did not prolong coagulation time even at the dose which exerted significant antithrombotic effects, while it decreased TAT level in plasma in a dose-dependent manner. YM-75466 exerted anti-FXa activity but not anti-thrombin activity.  YM-75466, unlike heparin, exerts its antithrombotic effect through specific inhibition of FXa without any effect on thrombin.

YM-60828 (MsOH salt)

209187-02-0: YM-60828, also known as MsOH salt, is a chemical compound that belongs to a class of substances known for their potential therapeutic applications, particularly in the field of medicinal chemistry. It is characterized by its unique molecular structure, which includes specific functional groups that contribute to its biological activity. The compound is typically studied for its effects on various biological pathways, and it may exhibit properties such as anti-inflammatory or analgesic effects, depending on its mechanism of action. YM-60828 is often evaluated in preclinical studies to assess its pharmacokinetics, efficacy, and safety profile. As with many compounds in drug development, its solubility, stability, and interaction with biological targets are critical factors that influence its potential as a therapeutic agent. Researchers continue to explore its applications and optimize its properties for better performance in clinical settings.

YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.

CAS 209187-02-0

YM-60828 (MsOH salt)

YM-75466

Ref: TM-T29190