CAS 20925-27-3

4-Amino-2-chlorobenzonitrile

Description:

4-Amino-2-chlorobenzonitrile, with the CAS number 20925-27-3, is an organic compound characterized by the presence of an amino group (-NH2) and a cyano group (-C≡N) attached to a chlorinated benzene ring. This compound typically appears as a solid and is soluble in polar organic solvents. The amino group contributes to its basicity, while the cyano group enhances its reactivity, making it a useful intermediate in organic synthesis. The chlorine atom introduces additional reactivity and can influence the compound's physical properties, such as melting and boiling points. 4-Amino-2-chlorobenzonitrile is often utilized in the synthesis of pharmaceuticals, agrochemicals, and dyes due to its ability to participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose health risks if ingested or inhaled. Proper safety protocols should be followed when working with this substance in a laboratory setting.

Formula: C₇H₅ClN₂

InChI: InChI=1S/C7H5ClN2/c8-7-3-6(10)2-1-5(7)4-9/h1-3H,10H2

InChI key: InChIKey=ZFBKYGFPUCUYIF-UHFFFAOYSA-N

SMILES: C(#N)C1=C(Cl)C=C(N)C=C1

Synonyms:

• (3-Chloro-4-cyanophenyl)amine
• 2-Chloro-4-aminobenzonitrile
• 3-Chloro-4-cyanoaniline
• Benzonitrile, 4-Amino-2-Chloro-
• 4-Amino-2-chlorobenzonitrile

4-Amino-2-chlorobenzonitrile

CAS: 20925-27-3

Formula: C₇H₅ClN₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 152.58

Ref: 3B-A2784

4-Amino-2-chlorobenzonitrile, 97+%

CAS: 20925-27-3

4-Amino-2-chlorobenzonitrile is commonly used as an organic reagent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU refe

Formula: C₇H₅ClN₂

Purity: 97+%

Color and Shape: Powder or lumps, Yellow to pale brown

Molecular weight: 152.58

Ref: 02-L15924

Benzonitrile, 4-amino-2-chloro-

CAS: 20925-27-3

Formula: C₇H₅ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 152.5810

Ref: IN-DA002K53

4-Amino-2-chlorobenzonitrile

CAS: 20925-27-3

4-Amino-2-chlorobenzonitrile

Formula: C₇H₅ClN₂

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 152.58g/mol

Ref: 54-OR5293

4-Amino-2-chlorobenzonitrile

CAS: 20925-27-3

4-Amino-2-chlorobenzonitrile (4ACB) is a copper salt that can be used in antimalarial therapy. It has been shown to have strong antiplasmodial activity against the parasite Plasmodium falciparum and other species of the genus Plasmodium. 4ACB is synthesized by nitro group reduction and ammonolysis, followed by an addition reaction with chloroformate. 4ACB binds to the enzyme ferredoxin reductase and inhibits electron transfer, which leads to inhibition of ATP production and cell death. The molecular modelling study showed that 4ACB is a reactive molecule with high affinity constants for copper ion.

Formula: C₇H₅ClN₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 152.58 g/mol

Ref: 3D-FA46636

4-Amino-2-chlorobenzonitrile

CAS: 20925-27-3

Formula: C₇H₅ClN₂

Purity: 98%

Color and Shape: Solid, Beige powder

Molecular weight: 152.58

Ref: 10-F214572