CAS 209253-67-8

Eplerenone EP Impurity A

CAS: 209253-67-8

Formula: C₂₃H₂₈O₅

Color and Shape: Pale Yellow Solid

Molecular weight: 384.47

Ref: 4Z-E-139

(7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone

Controlled Product

CAS: 209253-67-8

Applications (7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone is an eplerenone (E588775) impurity. Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),

Formula: C₂₃H₂₈O₅

Color and Shape: Neat

Molecular weight: 384.47

Ref: TR-D453900

Eplerenone EP Impurity A

CAS: 209253-67-8

Formula: C₂₃H₂₈O₅

Molecular weight: 384.47

Ref: ST-EA-CP-E37001

(7Alpha,17Alpha)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid di-gamma-lactone

CAS: 209253-67-8

(7Alpha,17Alpha)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid di-gamma-lactone is a synthetic analogue of progesterone. It is used as a drug product for research and development purposes. The product has been shown to be metabolized through the 3beta hydroxysteroid dehydrogenase pathway or the side chain cleavage enzyme pathways. This product has not been evaluated in humans and should not be used for any human applications. (7Alpha,17Alpha)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21 -dicarboxylic acid di gamma lactone is an impurity standard for HPLC analysis of progesterone in urine.

Formula: C₂₃H₂₈O₅

Purity: Min. 95%

Molecular weight: 384.50 g/mol

Ref: 3D-JIA25367