CAS 209394-27-4

Ladostigil

Description:

Ladostigil, with the CAS number 209394-27-4, is a novel compound that has garnered interest primarily for its potential neuroprotective properties. It is classified as a dual inhibitor of both monoamine oxidase (MAO) and acetylcholinesterase (AChE), which are enzymes involved in the metabolism of neurotransmitters. This dual action suggests that Ladostigil may be beneficial in the treatment of neurodegenerative diseases, such as Alzheimer's disease, by enhancing cholinergic function and modulating oxidative stress. The compound is also noted for its ability to cross the blood-brain barrier, which is crucial for its therapeutic efficacy in central nervous system disorders. Additionally, Ladostigil has been studied for its potential anti-inflammatory effects and its role in promoting neurogenesis. Its safety profile and pharmacokinetics are subjects of ongoing research, making it a compound of significant interest in the field of neuropharmacology. Overall, Ladostigil represents a promising avenue for developing treatments aimed at cognitive decline and related neurological conditions.

Formula: C₁₆H₂₀N₂O₂

InChI: InChI=1S/C16H20N2O2/c1-4-10-17-15-9-7-12-6-8-13(11-14(12)15)20-16(19)18(3)5-2/h1,6,8,11,15,17H,5,7,9-10H2,2-3H3/t15-/m1/s1

InChI key: InChIKey=LHXOCOHMBFOVJS-OAHLLOKOSA-N

SMILES: N(CC#C)[C@H]1C=2C(CC1)=CC=C(OC(N(CC)C)=O)C2

Synonyms:

• (3R)-3-(Prop-2-ynylamino)indan-5-yl ethyl(methyl)carbamate
• Carbamic acid, ethylmethyl-, (3R)-2,3-dihydro-3-(2-propynylamino)-1H-inden-5-yl ester
• Ladostigil
• carbamic acid, N-ethyl-N-methyl-, (3R)-2,3-dihydro-3-(2-propyn-1-ylamino)-1H-inden-5-yl ester

Carbamic acid, N-ethyl-N-methyl-, (3R)-2,3-dihydro-3-(2-propyn-1-ylamino)-1H-inden-5-yl ester

CAS: 209394-27-4

Formula: C₁₆H₂₀N₂O₂

Purity: 95%

Molecular weight: 272.3422

Ref: IN-DA002K7A

Ladostigil

CAS: 209394-27-4

Ladostigil

Purity: ≥95%

Molecular weight: 272.34g/mol

Ref: 54-BUP12388

Ladostigil

CAS: 209394-27-4

Ladostigil is an oral cholinesterase & MAO-B inhibitor used for depression and Alzheimer's studies.

Formula: C₁₆H₂₀N₂O₂

Purity: 98.49%

Color and Shape: Solid

Molecular weight: 272.34

Ref: TM-T32535