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CAS 209394-46-7

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Ladostigil tartrate

Description:
Ladostigil tartrate, identified by its CAS number 209394-46-7, is a chemical compound that serves as a selective inhibitor of the enzyme monoamine oxidase (MAO), particularly the MAO-B subtype. It is primarily investigated for its potential neuroprotective effects and therapeutic applications in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. The compound is a derivative of the well-known drug selegiline, designed to enhance its efficacy and reduce side effects. Ladostigil exhibits antioxidant properties and may influence neurotransmitter levels, including dopamine and serotonin, contributing to its neuroprotective profile. The tartrate salt form enhances its solubility and stability, making it suitable for pharmaceutical formulations. Research into Ladostigil tartrate continues to explore its mechanisms of action, pharmacokinetics, and potential benefits in cognitive function and mood regulation. As with any pharmacological agent, understanding its safety profile, dosage, and interactions with other medications is crucial for its clinical application.
Formula:C16H20N2O2C4H6O6
InChI:InChI=1S/C16H20N2O2.C4H6O6/c1-4-10-17-15-9-7-12-6-8-13(11-14(12)15)20-16(19)18(3)5-2;5-1(3(7)8)2(6)4(9)10/h1,6,8,11,15,17H,5,7,9-10H2,2-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t15-;1-,2-/m11/s1
InChI key:InChIKey=DZMNQRCPJKPTNC-KBYGAXRISA-N
SMILES:N(CC#C)[C@H]1C=2C(CC1)=CC=C(OC(N(CC)C)=O)C2.[C@@H]([C@H](C(O)=O)O)(C(O)=O)O
Synonyms:
  • (3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (2:1)
  • Carbamic acid, N-ethyl-N-methyl-, (3R)-2,3-dihydro-3-(2-propyn-1-ylamino)-1H-inden-5-yl ester, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
  • Carbamic acid, ethylmethyl-, (3R)-2,3-dihydro-3-(2-propynylamino)-1H-inden-5-yl ester, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
  • Ethylmethyl-carbamic acid (3R)-2,3-dihydro-3-(2-propynylamino)-1H-inden-5-yl ester (2R,3R)-2,3-dihydroxybutanedioate (2:1)
  • Tv 3326
  • Ladostigil tartrate
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