CAS 209414-27-7: (αS)-2-Amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol

Description: (αS)-2-Amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol, with CAS number 209414-27-7, is a chemical compound characterized by its complex structure, which includes an amino group, a chloro substituent, and a trifluoromethyl group attached to a benzene ring. The presence of the cyclopropylethynyl group contributes to its unique reactivity and potential applications in medicinal chemistry. This compound is likely to exhibit specific stereochemical properties due to its chiral center, influencing its biological activity and interactions with biological targets. The trifluoromethyl group is known for enhancing lipophilicity and metabolic stability, which can be advantageous in drug design. Additionally, the compound's solubility, stability, and reactivity can be influenced by the functional groups present, making it a subject of interest for further research in pharmacology and organic synthesis. Overall, this compound's intricate structure and functional groups suggest potential utility in various chemical and pharmaceutical applications.

Formula: C₁₃H₁₁ClF₃NO

InChI: InChI=1S/C13H11ClF3NO/c14-9-3-4-11(18)10(7-9)12(19,13(15,16)17)6-5-8-1-2-8/h3-4,7-8,19H,1-2,18H2/t12-/m0/s1

InChI key: InChIKey=KEMUGFRERPPUHB-LBPRGKRZSA-N

SMILES: FC(F)(F)C(O)(C#CC1CC1)C2=CC(Cl)=CC=C2N

Synonyms:

• (2S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
• (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol
• (S)-5-Chloro-alpha-(cyclopropylethynyl)-2-amino-alpha-(trifluoromethyl)-benzenemethanol
• (αS)-2-Amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol
• (αS)-2-Amino-5-chloro-α-(cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol
• Benzenemethanol, 2-amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)-, (αS)-
• Benzenemethanol, 2-amino-5-chloro-α-(cyclopropylethynyl)-α-(trifluoromethyl)-, (αS)-
• E03
• E6
• Sd 573
• (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol

Efavirenz Related Compound A ((S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol)

CAS: 209414-27-7

Amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and …

• Formula: C₁₃H₁₁NOF₃Cl
• Color and Shape: White Powder
• Molecular weight: 289.04813

Benzenemethanol, 2-amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)-, (αS)-

CAS: 209414-27-7

• Formula: C₁₃H₁₁ClF₃NO
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 289.6807

Efavirenz USP Related Compound A

CAS: 209414-27-7

• Formula: C₁₃H₁₁ClF₃NO
• Molecular weight: 289.68

(2R)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol

CAS: 209414-27-7

• Molecular weight: 289.68075g/mol

Efavirenz USP Related Compound A

CAS: 209414-27-7

• Formula: C₁₃H₁₁ClF₃NO
• Color and Shape: Neat
• Molecular weight: 289.68

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol

CAS: 209414-27-7

Applications Intermediate in the preparation of Efavirenz (E425000) impurity.

• Formula: C₁₃H₁₁ClF₃NO
• Color and Shape: Neat
• Molecular weight: 289.68

(S)-2-(2-Amino-5-chloro-phenyl)-4-cyclopropyl-1,1,1-trifluoro-but-3-yn-2-ol

CAS: 209414-27-7

• Purity: 95+%
• Molecular weight: 289.67999267578125

(S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol

CAS: 209414-27-7

Please enquire for more information about (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol including the price, delivery time and more detailed …

• Formula: C₁₃H₁₁ClF₃NO
• Purity: Min. 95%
• Molecular weight: 289.68 g/mol