CAS 2095-62-7

7-Hydroxychlorpromazine

Description:

7-Hydroxychlorpromazine is a derivative of chlorpromazine, which is an antipsychotic medication primarily used to treat schizophrenia and other mental health disorders. This compound is characterized by the presence of a hydroxyl group at the 7-position of the chlorpromazine structure, which influences its pharmacological properties. It is typically a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. The molecular formula reflects its complex structure, which includes a tricyclic ring system and a chlorine atom, contributing to its biological activity. As a metabolite of chlorpromazine, 7-hydroxychlorpromazine may exhibit varying degrees of antipsychotic effects, and its presence in biological systems can be indicative of chlorpromazine metabolism. The compound is of interest in pharmacological research, particularly in understanding the metabolic pathways of antipsychotic drugs and their potential therapeutic effects or side effects. Safety and handling precautions are essential due to its pharmacological activity.

Formula: C₁₇H₁₉ClN₂OS

InChI: InChI=1S/C17H19ClN2OS/c1-19(2)8-3-9-20-14-6-5-13(21)11-17(14)22-16-7-4-12(18)10-15(16)20/h4-7,10-11,21H,3,8-9H2,1-2H3

InChI key: InChIKey=HICFFJZGXWEIHN-UHFFFAOYSA-N

SMILES: C(CCN(C)C)N1C=2C(SC=3C1=CC(Cl)=CC3)=CC(O)=CC2

Synonyms:

• 10H-Phenothiazin-3-ol, 8-chloro-10-[3- (dimethylamino)propyl]-
• 7-Hydroxy-2-chloropromazine
• 7-Hydroxychlorpromazine
• NSC 131053
• Phenothiazin-3-ol, 8-chloro-10-[3- (dimethylamino)propyl]-
• 8-Chloro-10-[3-(dimethylamino)propyl]-10H-phenothiazin-3-ol

7-Hydroxy Chlorpromazine

CAS: 2095-62-7

Formula: C₁₇H₁₉ClN₂OS

Color and Shape: Off-White Solid

Molecular weight: 334.86

Ref: 4Z-C-125003

7-Hydroxy Chlorpromazine-d6

CAS: 2095-62-7

Formula: C₁₇H₁₃D₆ClN₂OS

Color and Shape: Off-White Solid

Molecular weight: 340.91

Ref: 4Z-C-125004

7-Hydroxy Chlorpromazine-d6 Hydrochloride

Controlled Product

CAS: 2095-62-7

Applications Labelled analogue of 7-Hydroxychlorpromazine, the 7-hydroxy analogue and a major metabolite of the atypical antipsychotic Chlorpromazine (C424750).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jori, A. et al.: Int. J. Neuropharmacol., 5, 435 (1966); Shavit, S. et al.: Comm. Psychopharmacol., 4, 495 (1980);

Formula: C₁₇H₁₄D₆Cl₂N₂OS

Color and Shape: Neat

Molecular weight: 377.36

Ref: TR-H825067

7-hydroxychlorpromazine

CAS: 2095-62-7

7-Hydroxychlorpromazine, an active metabolite of Chlorpromazine, can reversibly counteract the suppression of regionally dense dopaminergic neurons induced by Amphetamine.

Formula: C₁₇H₁₉ClN₂OS

Color and Shape: Solid

Molecular weight: 334.86

Ref: TM-T201496