P5 ligand, associated with DnaK and DnaJ, is a small molecule known for its role in modulating the activity of heat shock proteins, specifically chaperones involved in protein folding and stress response. The compound is characterized by its ability to bind to the ATPase domain of DnaK, thereby influencing its chaperone activity. This interaction can enhance the protein's ability to assist in the proper folding of other proteins, particularly under stress conditions. P5 ligand is often studied in the context of bacterial stress responses and has potential implications in understanding bacterial survival mechanisms and developing antimicrobial strategies. Its chemical structure includes specific functional groups that facilitate binding to the target proteins, contributing to its efficacy as a modulator. The CAS number 209518-24-1 uniquely identifies this compound in chemical databases, allowing for precise referencing in scientific literature. Overall, P5 ligand represents a significant tool in biochemical research, particularly in the study of molecular chaperones and their roles in cellular stress responses.

p5 Ligand for Dnak and DnaJ

209518-24-1: P5 ligand, associated with DnaK and DnaJ, is a small molecule known for its role in modulating the activity of heat shock proteins, specifically chaperones involved in protein folding and stress response. The compound is characterized by its ability to bind to the ATPase domain of DnaK, thereby influencing its chaperone activity. This interaction can enhance the protein's ability to assist in the proper folding of other proteins, particularly under stress conditions. P5 ligand is often studied in the context of bacterial stress responses and has potential implications in understanding bacterial survival mechanisms and developing antimicrobial strategies. Its chemical structure includes specific functional groups that facilitate binding to the target proteins, contributing to its efficacy as a modulator. The CAS number 209518-24-1 uniquely identifies this compound in chemical databases, allowing for precise referencing in scientific literature. Overall, P5 ligand represents a significant tool in biochemical research, particularly in the study of molecular chaperones and their roles in cellular stress responses.

<p>P5 is a nonapeptide ligand for DnaK/DnaJ, mimicking the key sites of mitochondrial aspartate aminotransferase presequence.</p>

CAS 209518-24-1

p5 Ligand for Dnak and DnaJ

p5 Ligand for Dnak and DnaJ

Ref: TM-TP1496