CAS 2095417-26-6

2'-O-Methyl-5-methyl-4-thiouridine

Description:

2'-O-Methyl-5-methyl-4-thiouridine is a modified nucleoside that features several distinctive characteristics. It is a derivative of uridine, where the 2'-hydroxyl group is methylated, and a sulfur atom replaces the oxygen at the 4-position, contributing to its unique properties. This modification enhances the stability of the nucleoside against enzymatic degradation, making it particularly useful in various biochemical applications, including RNA synthesis and therapeutic development. The presence of the methyl group at the 5-position can influence the nucleoside's interaction with RNA polymerases and its incorporation into RNA strands. Additionally, the thiol group may impart unique chemical reactivity and biological activity, potentially affecting the nucleoside's role in cellular processes. Overall, 2'-O-Methyl-5-methyl-4-thiouridine is of interest in the fields of molecular biology and medicinal chemistry due to its modified structure, which can enhance the efficacy and stability of RNA-based therapeutics.

Formula: C₁₁H₁₆N₂O₅S

Synonyms:

• 2'-O-Methyl-5-methyl-4-thiouridine

2'-O-Methyl-5-methyl-4-thiouridine

CAS: 2095417-26-6

Nucleoside Derivatives - Thio-nucleosides, 2’-Modified nucleosides, 5-Modified pyrimidine nucleosides

Formula: C₁₁H₁₆N₂O₅S

Color and Shape: Solid

Molecular weight: 288.32

Ref: TM-TNU0238