CAS 2095432-47-4

EPZ020411 HCl

CAS: 2095432-47-4

EPZ020411: potent, selective PRMT6 inhibitor, good bioavailability in rats, enhances radiotherapy in GSC brain tumors.

Formula: C₂₅H₄₀Cl₂N₄O₃

Color and Shape: Solid

Molecular weight: 515.52

Ref: TM-T69922

N1,N2-Dimethyl-N1-((3-(4-((1R,3R)-3-(2-(tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutoxy)phenyl)-1H-pyrazol-4-yl)methyl)ethane-1,2-diamin e dihydrochloride

CAS: 2095432-47-4

(1R,3R)-3-(2-(Tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutanol is a potent and selective activator of the GABAA receptor. It is a beta blocker that inhibits the binding of GABA to the GABA receptor. The potency of (1R,3R)-3-(2-(tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutanol at the GABAA receptor has been shown in rat cortical membranes and calf thymus DNA. (1R,3R)-3-(2-(Tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutanol is a specific ligand for the alpha subunit of GABA receptors, which are ligand gated ion channels that are important for regulating neuronal excitability. The synthesis of (1R,3R)-3

Formula: C₂₅H₄₀Cl₂N₄O₃

Purity: Min. 95%

Molecular weight: 515.5 g/mol

Ref: 3D-VID43247