CAS 2095677-20-4

eIF4A3-IN-2

CAS: 2095677-20-4

eIF4A3-IN-2 is a small molecule inhibitor targeting eIF4A3, which is a DEAD-box RNA helicase. This compound is synthesized from a chemical library designed to modulate RNA-binding proteins. Its mode of action involves binding to eIF4A3 to inhibit its helicase activity, thereby disrupting the process of nonsense-mediated mRNA decay and pre-mRNA splicing. This specific inhibition is particularly valuable for exploring the regulation of gene expression at the post-transcriptional level.

Formula: C₂₅H₁₉Br₂ClN₄O₂

Purity: Min. 95%

Molecular weight: 602.7 g/mol

Ref: 3D-VID67720

eIF4A3-IN-2

CAS: 2095677-20-4

eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.

Formula: C₂₅H₁₉Br₂ClN₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 602.71

Ref: TM-T11171