CAS 2095732-06-0

(3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid Dihydrochloride

Controlled Product

CAS: 2095732-06-0

Formula: C₁₁H₂₂BN₃O₅•2(HCl)

Color and Shape: Neat

Molecular weight: 323.14193

Ref: TR-A310680

Numidargistat

CAS: 2095732-06-0

CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).

Formula: C₁₁H₂₂BN₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 287.12

Ref: TM-T10692L

CB-1158

CAS: 2095732-06-0

CB-1158 is an arginase inhibitor, which is a small molecule derived from a synthetic source designed to modulate immune functions. Its mode of action involves the inhibition of the arginase enzyme, a key player in the urea cycle responsible for the hydrolysis of arginine into ornithine and urea. By blocking arginase, CB-1158 effectively prevents the depletion of extracellular arginine, a vital amino acid required for the activation and proliferation of T cells within the immune system. This inhibition leads to enhanced immune responses against tumors.

Formula: C₁₁H₂₂BN₃O₅

Purity: Min. 95%

Molecular weight: 287.12 g/mol

Ref: 3D-VID73206