CAS 20964-06-1

5-Carboxymethyluridine

Description:

5-Carboxymethyluridine is a modified nucleoside that is derived from uridine, featuring a carboxymethyl group at the 5-position of the uracil base. This compound is characterized by its unique structural modifications, which can influence its biochemical properties and interactions. It is soluble in water, making it suitable for various biological applications. The presence of the carboxymethyl group enhances its polarity and can affect its binding affinity to nucleic acid structures and proteins. 5-Carboxymethyluridine is of interest in biochemical research, particularly in studies related to RNA modification and the role of nucleoside derivatives in cellular processes. Its potential applications include use in therapeutic development and as a tool in molecular biology for studying RNA dynamics. As with many nucleoside analogs, understanding its behavior in biological systems is crucial for elucidating its functional roles and potential therapeutic benefits.

Formula: C₁₁H₁₄N₂O₈

InChI: InChI=1S/C11H14N2O8/c14-3-5-7(17)8(18)10(21-5)13-2-4(1-6(15)16)9(19)12-11(13)20/h2,5,7-8,10,14,17-18H,1,3H2,(H,15,16)(H,12,19,20)/t5-,7-,8-,10-/m1/s1

InChI key: InChIKey=FAWQJBLSWXIJLA-VPCXQMTMSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C=C(CC(O)=O)C(=O)NC2=O

Synonyms:

• 1,2,3,4-Tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-5-pyrimidineacetic acid
• 5-Carboxymethyluridine
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5-Uridineacetic acid
• Uridine, 5-(Carboxymethyl)-
• 1,2,3,4-Tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetic acid
• 5-(Carboxymethyl)uridine
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-

5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-

CAS: 20964-06-1

Formula: C₁₁H₁₄N₂O₈

Purity: 97%

Color and Shape: Solid

Molecular weight: 302.2375

Ref: IN-DA002KCE

Uridine-5-acetic acid

CAS: 20964-06-1

Uridine-5-acetic acid

Purity: ≥98%

Molecular weight: 302.24g/mol

Ref: 54-BUP20116

Uridine-5-acetic acid

CAS: 20964-06-1

Uridine-5-acetic acid (5-Carboxymethyluridine) is a nucleoside formed during RNA transfer processes in yeast and wheat embryos.

Formula: C₁₁H₁₄N₂O₈

Purity: 99.59%

Color and Shape: Solid

Molecular weight: 302.24

Ref: TM-TNU0046

5-(Carboxymethyl)uridine

CAS: 20964-06-1

5-(Carboxymethyl)uridine is an uridine compound that has been shown to inhibit protein synthesis in cultured cells. It binds to the ribosome and inhibits protein synthesis by inhibiting the formation of peptide bonds. 5-Carboxymethyl-uridine has been shown to be effective against two strains of bacteria, Escherichia coli and Staphylococcus aureus, in cell culture experiments. The inhibition of bacterial protein synthesis was shown to be dose-dependent for both strains. The mechanism of action is believed to be due to its binding to the ribosome and inhibiting the formation of peptide bonds.

Formula: C₁₁H₁₄N₂O₈

Purity: Min. 95 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 302.24 g/mol

Ref: 3D-NC159474

5-Uridineacetic Acid

Controlled Product

CAS: 20964-06-1

Formula: C₁₁H₁₄N₂O₈

Color and Shape: Neat

Molecular weight: 302.24

Ref: TR-U829935