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CAS 2097493-39-3

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  • PDE2 inhibitor 6
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    PDE2 inhibitor 6

    CAS:
    <p>PDE2 inhibitor6 (Compound 1) is an orally active phosphodiesterase (PDE) inhibitor, effectively inhibiting PDE2A, PDE3B, and PDE10A2 with IC50 values of 0.95 nM, 6.17 μM (pIC50=5.21), and 87.1 nM (pIC50=7.06), respectively. It modulates AMPA receptor activity, enhances synaptic plasticity, and improves learning and memory in rat models. Furthermore, PDE2 inhibitor6 possesses blood-brain barrier permeability.</p>
    Formula:C20H22F2N6O
    Color and Shape:Solid
    Molecular weight:400.425

    Ref: TM-T206498