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CAS 2097509-36-7

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Thalidomide-NH-PEG2-C2-NH2 (TFA)

Description:
Thalidomide-NH-PEG2-C2-NH2 (TFA) is a synthetic compound that combines thalidomide, a drug known for its immunomodulatory and anti-inflammatory properties, with a polyethylene glycol (PEG) moiety. The PEG segment enhances the solubility and bioavailability of the compound, while the amine groups (NH2) can facilitate further chemical modifications or conjugations. The presence of trifluoroacetic acid (TFA) indicates that the compound may be in its salt form, which can influence its stability and solubility in various solvents. Thalidomide itself has a complex history due to its teratogenic effects when used during pregnancy, but its derivatives are being explored for therapeutic applications in conditions like multiple myeloma and leprosy. The specific structure of Thalidomide-NH-PEG2-C2-NH2 suggests potential for targeted drug delivery systems, leveraging the PEGylation to improve pharmacokinetics. Overall, this compound represents a fusion of established pharmacological activity with modern drug delivery strategies, making it a subject of interest in pharmaceutical research.
Formula:C21H25F3N4O8
Synonyms:
  • Thalidomide-4-NH-PEG2-NH2 TFA
  • Thalidomide-PEG2-C2-NH2 (TFA)
  • Thalidomide-NH-PEG2-NH2 TFA
  • Thalidomide-NH-PEG2-C2-NH2 (TFA)
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