CAS 20977-05-3

Escin monosodium salt

Description:

Escin monosodium salt, with the CAS number 20977-05-3, is a glycoside derived from the seeds of the horse chestnut tree (Aesculus hippocastanum). It is primarily known for its anti-inflammatory and venotonic properties, making it useful in treating conditions related to venous insufficiency and edema. The substance is characterized by its ability to stabilize capillary walls, reduce permeability, and enhance lymphatic drainage. Escin monosodium salt is typically soluble in water, which facilitates its use in various pharmaceutical formulations. Its molecular structure includes a triterpene saponin component, contributing to its biological activity. Additionally, escin exhibits antioxidant properties, which may help in mitigating oxidative stress. Due to its natural origin and therapeutic benefits, escin monosodium salt is often incorporated into topical creams and oral supplements aimed at improving circulation and reducing swelling. Safety and efficacy profiles are well-documented, although potential side effects may include gastrointestinal disturbances in some individuals. Overall, escin monosodium salt is a valuable compound in both herbal medicine and modern pharmacology.

Formula: C₅₃H₈₂O₃₆S₄

InChI: InChI=1/C54H84O23.Na/c1-22(23(2)71-24(3)57)45(68)70-21-54-26-16-49(4,5)43(42(54)65)73-32(54)17-53(9)25(26)10-11-30-50(6)14-13-31(51(7,20-56)29(50)12-15-52(30,53)8)74-48-40(76-46-36(62)33(59)27(58)19-69-46)38(64)39(41(77-48)44(66)67)75-47-37(63)35(61)34(60)28(18-55)72-47;/h10,22-23,26-43,46-48,55-56,58-65H,11-21H2,1-9H3,(H,66,67);/q;+1/t22?,23?,26?,27-,28-,29?,30?,31?,32-,33+,34-,35+,36-,37-,38+,39+,40-,41+,42?,43-,46+,47-,48-,50?,51-,52?,53-,54?;/m1./s1

SMILES: CC(C(C)OC(=O)C)C(=O)OCC12C3CC(C)(C)C(C2O)OC1CC1(C)C3=CCC2C3(C)CCC(C(C)(CO)C3CCC12C)OC1C(C(C(C(C(=O)O)O1)OC1C(C(C(C(CO)O1)O)O)O)O)OC1C(C(C(CO1)O)O)O.[Na]

Synonyms:

• Aescin sodium
• Escin sodium
• Sodium Aescinate
• Sodium escin
• Sodium escinate
• butanoic acid, 3-(acetyloxy)-2-methyl-, (5xi,8xi,9xi,10xi,16alpha,17xi,18xi,21beta)-16,21-epoxy-3-[[O-alpha-D-glucopyranosyl-(1->4)-O-[beta-D-xylopyranosyl-(1->2)]-beta-D-glucopyranuronosyl]oxy]-22,24-dihydroxyolean-12-en-28-yl ester, monosodium salt
• Escin, monosodium salt
• Escin, monosodium salt
• Sodium Aescinate for Injection
• Escin, Mononatriumsalz
• Escin, monosodium salt USP/EP/BP
• Aescin monosodium salt
• Aescin polysulphate sodium salt
• Escin sodium salt
• Sodium Aescine

Escin, monosodium salt

CAS: 20977-05-3

Formula: C₅₄H₈₄NaO₂₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 1124.2207

Ref: IN-DA002KEG

Sodium Aescinate

CAS: 20977-05-3

Formula: C₅₄H₈₄NaO₂₃

Purity: 95%~99%

Molecular weight: 1124.23

Ref: BP-BP3368

Sodium Aescinate

CAS: 20977-05-3

Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.

Formula: C₅₄H₈₃NaO₂₃

Purity: 95.17%

Color and Shape: Solid

Molecular weight: 1123.21

Ref: TM-T3027

Aescin monosodium salt

CAS: 20977-05-3

Aescin monosodium salt is a semisynthetic, anti-inflammatory product derived from escin, which is a mixture of saponins extracted from horse chestnut seeds (Aesculus hippocastanum). It functions primarily by enhancing the integrity of venous walls and decreasing vascular permeability. This is achieved through the stabilization of lysosomal membranes and the inhibition of enzymes that contribute to the breakdown of the vascular endothelium, as well as promoting the release of prostaglandins with vasoprotective properties.

Formula: C₅₅H₈₆NaO₂₄

Purity: Min. 95%

Molecular weight: 1,154.25 g/mol

Ref: 3D-OA137562

Aescin polysulphate sodium salt

CAS: 20977-05-3

Aescin polysulphate sodium salt is a synthetic anti-inflammatory compound, designed as an enhanced version of the natural saponin, aescin, derived from horse chestnut seeds (Aesculus hippocastanum). The modification to create the polysulphate sodium salt increases the solubility and bioavailability of the compound, facilitating its absorption and effectiveness in biological systems.

Formula: C₅₃H₈₂O₃₆S₄

Purity: Min. 95%

Molecular weight: 1,423.46 g/mol

Ref: 3D-OA11465