CAS 20980-22-7

2-(1-Piperazinyl)pyrimidine

Description:

2-(1-Piperazinyl)pyrimidine is a heterocyclic organic compound characterized by the presence of a pyrimidine ring substituted with a piperazine moiety. This compound features a six-membered piperazine ring, which contains two nitrogen atoms, and a pyrimidine ring, which is a six-membered ring containing two nitrogen atoms at the 1 and 3 positions. The presence of these nitrogen atoms contributes to its basicity and potential for forming hydrogen bonds, making it a versatile building block in medicinal chemistry. It is often investigated for its biological activity, particularly in the development of pharmaceuticals, due to its ability to interact with various biological targets. The compound is typically a solid at room temperature and may exhibit moderate solubility in polar solvents. Its structure allows for potential modifications that can enhance its pharmacological properties, making it a subject of interest in drug design and development. Safety and handling precautions should be observed, as with any chemical substance, due to potential toxicity or reactivity.

Formula: C₈H₁₂N₄

InChI: InChI=1/C8H12N4/c1-2-10-8(11-3-1)12-6-4-9-5-7-12/h1-3,9H,4-7H2/p+1

InChI key: InChIKey=MRBFGEHILMYPTF-UHFFFAOYSA-N

SMILES: C=1(N=CC=CN1)N2CCNCC2

Synonyms:

• 1-(2-Pyrimidinyl)piperazine
• 1-(2-Pyrimidyl)piperazine
• 1-(2-Pyrimidyl)piperazine dihydrochloride
• 1-(2-Pyrimimidinyl)Piperazine
• 1-(4-Pyrimidin-2-yl)piperazine
• 1-(Pyrimidin-2-yl)piperazine
• 2-(1-Piperazino)pyrimidine
• 2-(Piperazin-1-Yl)Pyrimidine
• 2-Piperazino-Pyrimidine
• 2-Piperazinopyrimidine
• 4-(2-Pyrimidinyl)piperazine
• 4-Pyrimidin-2-Ylpiperazin-1-Ium
• Cm 56324H
• Mj 13653
• N-(2-Pyrimidinyl)-piperazine
• N-(2-Pyrimidyl)piperazine
• N-2-Pyrimidinylpiperazine
• Pyrimidine, 2-(1-piperazinyl)-
• 2-(1-Piperazinyl)pyrimidine
• LABOTEST-BB LT00233196
• TIMTEC-BB SBB003913
• 1-PYRIMIDYL PIPERAZINE
• mj13653
• 2-(1-piperazinyl)-pyrimidin
• 1-pp
• 1-Pyrimydinyl Piperazine
• AKOS BBS-00003690
• RARECHEM AH CK 0195
• 2-PIPERAZIN-1-YLPYRIMIDINE
• PMPRZ

1-(2-Pyrimidyl)piperazine

CAS: 20980-22-7

Formula: C₈H₁₂N₄

Purity: >98.0%(GC)(T)

Color and Shape: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Molecular weight: 164.21

Ref: 3B-P1110

Pyrimidine, 2-(1-piperazinyl)-

CAS: 20980-22-7

Formula: C₈H₁₂N₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 164.2077

Ref: IN-DA002KF5

2-(1-Piperazinyl)pyrimidine

CAS: 20980-22-7

2-(1-Piperazinyl)pyrimidine is used as an anti-anxiety drug.

Formula: C₈H₁₂N₄

Purity: 98.46%

Color and Shape: Liquid - Crystal - Lump

Molecular weight: 164.21

Ref: TM-T1696

2-(1-Piperazinyl)pyrimidine

CAS: 20980-22-7

2-(1-Piperazinyl)pyrimidine

Purity: ≥98%

Molecular weight: 164.21g/mol

Ref: 54-BUP19265

Buspirone EP Impurity A (Buspirone USP Related Compound A)

CAS: 20980-22-7

Formula: C₈H₁₂N₄

Color and Shape: Pale Yellow Liquid

Molecular weight: 164.21

Ref: 4Z-B-073

1-(2-Pyrimidyl)piperazine dihydrochloride

CAS: 20980-22-7

Formula: C₈H₁₂N₄

Molecular weight: 164.21

Ref: 7W-GK8989

2-(Piperazin-1-yl)pyrimidine

CAS: 20980-22-7

2-(Piperazin-1-yl)pyrimidine

Formula: C₈H₁₂N₄

Purity: 99%

Color and Shape: almost colourless fused solid (material may darken on storage)

Molecular weight: 164.21g/mol

Ref: 54-OR8006

Buspirone EP Impurity A

CAS: 20980-22-7

Formula: C₈H₁₂N₄

Molecular weight: 164.21

Ref: ST-EA-CP-B22001

2-(1-Piperazinyl)pyrimidine

CAS: 20980-22-7

Impurity Buspirone EP Impurity A
Applications 2-(1-Piperazinyl)pyrimidine (Buspirone EP Impurity A) is the major metabolite of Tandospirone (T006430).
References Goa, K., et al.: Drugs, 32, 114 (1986), Lamberg, T., et al.: Clin. Pharmacol. Ther., 63, 640 (1998), Niwa, T., et al.: Biol. Pharm. Bull 28, 1711 (2005), Natsui, K., et al.: Eur. J. Drug Metab. Pharmacokinet., 32, 233 (2007),

Formula: C₈H₁₂N₄

Color and Shape: Neat

Molecular weight: 164.21

Ref: TR-P481300

1-(2-Pyrimidyl)-piperazine

CAS: 20980-22-7

Formula: C₈H₁₂N₄

Purity: 97%

Color and Shape: Oil

Molecular weight: 164.212

Ref: 10-F009854

1-(2-Pyrimidyl)piperazine

CAS: 20980-22-7

1-(2-Pyrimidyl)piperazine is a compound that has been found to be present in human serum and urine. It is thought that 1-(2-Pyrimidyl)piperazine is involved in locomotor activity and the regulation of dopamine levels. It also has a structural similarity to 5-hydroxytryptamine (5-HT), which is known as a neurotransmitter that regulates mood, appetite, sleep, memory, and learning. This drug may have anti-inflammatory properties due to its ability to inhibit the release of growth factors.

Formula: C₈H₁₂N₄

Purity: Min. 95%

Molecular weight: 164.21 g/mol

Ref: 3D-FP05049

2-(1-Piperazinyl)pyrimidine, 99%

CAS: 20980-22-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₂N₄

Purity: 99%

Color and Shape: Clear, Powder or fused solid or liquid as melt

Molecular weight: 164.21

Ref: 02-L15884

Buspirone Related Compound A (2-(Piperazin-1-yl)pyrimidine)

CAS: 20980-22-7

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₈H₁₂N₄

Color and Shape: Clear Light Yellow Liquid

Molecular weight: 164.1062

Ref: 45-1078573