CAS 209984-56-5

N~2~-[(3,5-difluorophenyl)acetyl]-N-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide

Description:

The chemical substance known as N~2~-[(3,5-difluorophenyl)acetyl]-N-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide, with the CAS number 209984-56-5, is a complex organic compound characterized by its unique structural features. It contains a dibenzoazepine core, which contributes to its potential biological activity, particularly in pharmacological contexts. The presence of the difluorophenyl group suggests enhanced lipophilicity and may influence the compound's interaction with biological targets. Additionally, the L-alaninamide moiety indicates that it may exhibit properties related to amino acids, potentially affecting its solubility and reactivity. This compound is likely to be of interest in medicinal chemistry, possibly as a candidate for drug development, given its structural complexity and the presence of functional groups that can participate in various chemical interactions. Its specific properties, such as solubility, stability, and biological activity, would require empirical investigation to fully characterize its behavior in different environments.

Formula: C₂₆H₂₃F₂N₃O₃

InChI: InChI=1/C26H23F2N3O3/c1-15(29-23(32)13-16-11-17(27)14-18(28)12-16)25(33)30-24-21-9-4-3-7-19(21)20-8-5-6-10-22(20)31(2)26(24)34/h3-12,14-15,24H,13H2,1-2H3,(H,29,32)(H,30,33)/t15-,24-/m0/s1

SMILES: C[C@@H](C(=N[C@H]1c2ccccc2c2ccccc2N(C)C1=O)O)N=C(Cc1cc(cc(c1)F)F)O

Benzeneacetamide, N-​[(1S)​-​2-​[[(7S)​-​6,​7-​dihydro-​5-​methyl-​6-​oxo-​5H-​dibenz[b,​d]​azepin-​7-​yl]​amino]​-​1-​methyl-​2-​oxoethyl]​-​3,​5-​difluoro-

CAS: 209984-56-5

Formula: C₂₆H₂₃F₂N₃O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 463.4759

Ref: IN-DA002KI8

YO-01027

CAS: 209984-56-5

YO-01027

Purity: ≥95%

Molecular weight: 463.48g/mol

Ref: 54-BUP02007

YO-01027

CAS: 209984-56-5

YO-01027 (DBZ) is a potent γ-secretase inhibitor.

Formula: C₂₆H₂₃F₂N₃O₃

Purity: 97.21% - 99.58%

Color and Shape: Solid

Molecular weight: 463.48

Ref: TM-T6135

Dibenzazepine (Deshydroxy LY 411575)

Controlled Product

CAS: 209984-56-5

Applications Dibenzazepine (Deshydroxy LY 411575) is a dipeptidic γ-secretase inhibitor and anti-Alzheimer agent (1,2,3,4).
References (1) Weihofen, A., et al.: Science, 296, 2215 (2002) (2) Weihofen, A., et al.: J. Biol. Chem., 278, 16528 (2003) (3) Kan, T., et al.: Bioorg. Med. Chem. Lett., 14, 1983 (2004) (4) Krawitz, P., et al.: J. Biol. Chem., 280, 39515 (2005)

Formula: C₂₆H₂₃F₂N₃O₃

Color and Shape: Neat

Molecular weight: 463.48

Ref: TR-D422600

DBZ

CAS: 209984-56-5

Inhibitor of γ-secretase

Formula: C₂₆H₂₃F₂N₃O₃

Purity: Min. 95%

Molecular weight: 463.48 g/mol

Ref: 3D-FD21523