CAS 209984-57-6: (αS)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxybenzeneacetamide

Description: The chemical substance with the name "(αS)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxybenzeneacetamide" and CAS number "209984-57-6" is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a dibenzodiazepine core, which is known for its biological activity, particularly in pharmacology. The presence of difluoro and hydroxy groups suggests potential interactions with biological targets, enhancing its solubility and reactivity. The compound's structure indicates it may exhibit properties such as enzyme inhibition or receptor modulation, making it of interest in medicinal chemistry. Its stereochemical configuration, denoted by the (αS) and (1S) designations, implies that it may have specific interactions in biological systems, which can influence its efficacy and safety profile. Overall, this compound represents a class of molecules that could be explored for therapeutic applications, particularly in areas related to neurological or psychiatric disorders.

Formula: C₂₆H₂₃F₂N₃O₄

InChI: InChI=1S/C26H23F2N3O4/c1-14(29-25(34)23(32)15-11-16(27)13-17(28)12-15)24(33)30-22-20-9-4-3-7-18(20)19-8-5-6-10-21(19)31(2)26(22)35/h3-14,22-23,32H,1-2H3,(H,29,34)(H,30,33)/t14-,22-,23-/m0/s1

InChI key: InChIKey=ULSSJYNJIZWPSB-CVRXJBIPSA-N

SMILES: O=C(NC(C(=O)NC1C(=O)N(C=2C=CC=CC2C=3C=CC=CC31)C)C)C(O)C=4C=C(F)C=C(F)C4

Synonyms:

• (αS)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxybenzeneacetamide
• Ly 411,575
• Ly411575
• Benzeneacetamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxy-, (αS)-

Benzeneacetamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxy-, (αS)-

CAS: 209984-57-6

• Formula: C₂₆H₂₃F₂N₃O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 479.4753

LY-411575

CAS: 209984-57-6

• Purity: 98%
• Molecular weight: 479.48g/mol

LY-411575

CAS: 209984-57-6

• Purity: 98.05%
• Molecular weight: 479.48g/mol

LY-411575

CAS: 209984-57-6

• Formula: C₂₆H₂₃F₂N₃O₄
• Purity: >95.0%(HPLC)(qNMR)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 479.48

LY-411575

CAS: 209984-57-6

LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and …

• Formula: C₂₆H₂₃F₂N₃O₄
• Purity: 97.03% - 99.38%
• Color and Shape: Solid
• Molecular weight: 479.48

LY 411575

CAS: 209984-57-6

Potent inhibitor of γ-secretase. LY 411575 inhibited production of amyloid β (Aβ) peptides with IC50 …

• Formula: C₂₆H₂₃F₂N₃O₄
• Purity: Min. 95%
• Color and Shape: Solid
• Molecular weight: 479.48 g/mol