CAS 209984-68-9

(2S)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-2-hydroxy-3-methylbutanamide

Description:

The chemical substance with the name "(2S)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-2-hydroxy-3-methylbutanamide" and CAS number "209984-68-9" is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a dibenzodiazepine core, which is known for its biological activity, particularly in pharmacology. The presence of multiple chiral centers indicates that the compound can exist in different stereoisomeric forms, which may influence its biological properties and interactions. The functional groups, including amide and hydroxyl groups, suggest potential solubility in polar solvents and possible interactions with biological targets. This compound may be of interest in medicinal chemistry, particularly for its potential therapeutic applications. Its structural complexity and specific arrangement of atoms contribute to its unique chemical behavior and reactivity, making it a subject of study in drug development and related fields.

Formula: C₂₃H₂₇N₃O₄

InChI: InChI=1S/C23H27N3O4/c1-13(2)20(27)22(29)24-14(3)21(28)25-19-17-11-6-5-9-15(17)16-10-7-8-12-18(16)26(4)23(19)30/h5-14,19-20,27H,1-4H3,(H,24,29)(H,25,28)/t14-,19-,20-/m0/s1

InChI key: InChIKey=JURYTIUJMYPBNN-GKCIPKSASA-N

SMILES: N(C([C@@H](NC([C@H](C(C)C)O)=O)C)=O)[C@H]1C=2C(C=3C(N(C)C1=O)=CC=CC3)=CC=CC2

Synonyms:

• Butanamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-2-hydroxy-3-methyl-, (2S)-
• (2S)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-2-hydroxy-3-methylbutanamide
• LY 900009

LY900009

CAS: 209984-68-9

LY900009

Purity: ≥95%

Molecular weight: 409.48g/mol

Ref: 54-BUP08391

LY900009

CAS: 209984-68-9

LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.

Formula: C₂₃H₂₇N₃O₄

Purity: 97.07%

Color and Shape: Solid

Molecular weight: 409.48

Ref: TM-T9015

LY-900009

CAS: 209984-68-9

LY-900009 is a small molecule that inhibits the activity of the protease secretase. LY-900009 has been shown to inhibit the growth of breast cancer cells and increase survival rates in animal models. LY-900009 may be an important drug for treating solid tumours, especially those that are resistant to other therapies. LY-900009 was also found to be effective at preventing the regrowth of tumours after treatment with chemotherapy or radiotherapy. This agent has been shown to enhance the sensitivity of cancer cells to chemotherapy, by inhibiting β-catenin protein expression and cell cycle progression. It is also known to inhibit epidermal growth factor receptor (EGFR) signalling, which has been implicated in tumorigenesis.

Formula: C₂₃H₂₇N₃O₄

Purity: Min. 95%

Molecular weight: 409.49 g/mol

Ref: 3D-JIA98468