CAS 21003-46-3
:(8β,11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid
Description:
The chemical substance known as (8β,11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid, with the CAS number 21003-46-3, is a member of the prostaglandin family, which are bioactive lipids involved in various physiological processes. This compound features multiple hydroxyl groups, contributing to its polar nature and potential interactions with biological receptors. The presence of a keto group and a double bond in its structure indicates that it may participate in various biochemical pathways, including inflammation and regulation of vascular tone. Its stereochemistry, denoted by specific configurations at various carbon centers, is crucial for its biological activity, influencing how it interacts with enzymes and receptors in the body. Prostaglandins like this compound are often synthesized from arachidonic acid and play significant roles in mediating responses such as pain, fever, and immune responses. Understanding its characteristics can provide insights into its potential therapeutic applications and biological significance.
Formula:C20H34O5
InChI:InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16-,17+,19+/m0/s1
InChI key:InChIKey=GMVPRGQOIOIIMI-JCPCGATGSA-N
SMILES:C(CCCCCC(O)=O)[C@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)CC1=O
Synonyms:- (8β,11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid
- 11α,15-(S)-Dihydroxy-9-oxo-13-trans-8-isoprostenoic acid
- 21003-46-3
- 8-Iso-PGE<sub>1</sub>
- 8-Isoprostaglandin E<sub>1</sub>
- Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, stereoisomer
- Isoprostaglandin E<sub>1</sub>
- Ovinonic acid
- Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (8β,11α,13E,15S)-
- 8-Isoprostaglandin E1
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Found 5 products.
Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (8β,11α,13E,15S)-
CAS:Formula:C20H34O5Molecular weight:354.4818-iso Prostaglandin E1
CAS:<p>8-iso Prostaglandin E1 causes spasm in the pulmonary veins of dogs and also acts as a vasodilator.</p>Formula:C20H34O5Color and Shape:Light Yellow Crystalline SolidMolecular weight:354.488-Isoprostaglandin E1
CAS:Controlled Product<p>Applications 8-Isoprostaglandin E1 has vasodilatory and electrophysiological actions porcine coronary artery. It also inhibits acetylcholine release from parasympathetic nerves innervating guinea-pig trachea mediation by prostanoid EP3 receptors.<br>References Zhang Y., et al., J. Pharmacol. Exp. Ther.: 305, 1054-1060 (2003); Clarke D. L., et al., Br. J. Pharmacol.: 141, 600-609 (2004)<br></p>Formula:C20H34O5Color and Shape:NeatMolecular weight:354.481
