CAS 210110-90-0

3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)-

Description:

3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), with the CAS number 210110-90-0, is a chemical compound characterized by its piperidine ring structure, which is a six-membered saturated nitrogen-containing heterocycle. This compound features multiple hydroxyl (-OH) groups, specifically at the 3, 4, and 5 positions of the piperidine ring, contributing to its hydrophilicity and potential for hydrogen bonding. The presence of a butyl group and a hydroxymethyl group enhances its solubility in polar solvents and may influence its biological activity. As a hydrochloride salt, it is typically more stable and easier to handle than its free base form. The stereochemistry indicated by the (2R,3R,4R,5S) configuration suggests specific spatial arrangements of its substituents, which can significantly affect its pharmacological properties. This compound may have applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its structural features that can interact with biological targets.

Formula: C₁₀H₂₁NO₄·ClH

InChI: InChI=1S/C10H21NO4.ClH/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12;/h7-10,12-15H,2-6H2,1H3;1H/t7-,8+,9-,10-;/m1./s1

InChI key: InChIKey=QPAFAUYWVZMWPR-ZSOUGHPYSA-N

SMILES: C(CCC)N1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1.Cl

Synonyms:

• 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)-
• 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5S)-
• Miglustat HCl
• Miglustat hydrochloride

3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)-

CAS: 210110-90-0

Formula: C₁₀H₂₂ClNO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 255.7390

Ref: IN-DA002KL0

(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride

CAS: 210110-90-0

(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride

Purity: 98%

Color and Shape: Powder

Molecular weight: 255.74g/mol

Ref: 54-OR9100T

Miglustat hydrochloride

CAS: 210110-90-0

Miglustat hydrochloride

Purity: ≥98%

Molecular weight: 255.74g/mol

Ref: 54-BUP04566

Miglustat HCl

CAS: 210110-90-0

Formula: C₁₀H₂₁NO₄·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 219.28 36.46

Ref: 4Z-M-107001

N-(n-Butyl)-1-deoxynojirimycin hydrochloride

CAS: 210110-90-0

N-(n-Butyl)-1-deoxynojirimycin hydrochloride

Purity: >99%

Molecular weight: 255.74g/mol

Ref: 54-BICL4039

N-Butyldeoxynojirimycin hydrochloride

CAS: 210110-90-0

Ref: 7W-GC0520

N-Butyldeoxynojirimycin Hydrochloride

Controlled Product

CAS: 210110-90-0

Applications An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. N-Butyldeoxynojirimycin has recently been used to retard lipid storage in the central nervous system of an animal model of Tay-Sachs disease.1-Deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man.
References Hettkamp, H., et al.: Eur. J. Biochem., 142, 85 (1984), Szumilo, T., et al.: Arch. Biochem. Biophys., 247, 261 (1986), Fleet, G.W.J., et al.: FEBS Letters, 237, Number 1,2, 128 (1988), Kolter, T., et al.: Angew. Chem. Int. Ed. Engl., 36, 1955 (1997),

Formula: C₁₀H₂₁NO₄·ClH

Color and Shape: Neat

Molecular weight: 255.74

Ref: TR-B691000

N-Butyldeoxynojirimycin hydrochloride

CAS: 210110-90-0

Competitive inhibitor of ceramide-glycosyltransferase used for substrate reduction therapy in lysosomal storage disorders. It inhibits glucosylceramide synthase, which catalyses the initial step in glycosphingolipid biosynthetic pathway. This compound delays the onset of symptoms in type 1 Gaucher disease, Sandhoff disease and Tay-Sachs disease. It also reduces brain abnormalities in mucolipidosis type IV.

Formula: C₁₀H₂₁NO₄•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 255.74 g/mol

Ref: 3D-MB04673

Miglustat hydrochloride

CAS: 210110-90-0

Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher

Formula: C₁₀H₂₂ClNO₄

Purity: 99.85%

Color and Shape: Solid

Molecular weight: 255.74

Ref: TM-TQ0155