CAS 210110-90-0
:3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)-
Description:
3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), with the CAS number 210110-90-0, is a chemical compound characterized by its piperidine ring structure, which is a six-membered saturated nitrogen-containing heterocycle. This compound features multiple hydroxyl (-OH) groups, specifically at the 3, 4, and 5 positions of the piperidine ring, contributing to its hydrophilicity and potential for hydrogen bonding. The presence of a butyl group and a hydroxymethyl group enhances its solubility in polar solvents and may influence its biological activity. As a hydrochloride salt, it is typically more stable and easier to handle than its free base form. The stereochemistry indicated by the (2R,3R,4R,5S) configuration suggests specific spatial arrangements of its substituents, which can significantly affect its pharmacological properties. This compound may have applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its structural features that can interact with biological targets.
Formula:C10H21NO4·ClH
InChI:InChI=1S/C10H21NO4.ClH/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12;/h7-10,12-15H,2-6H2,1H3;1H/t7-,8+,9-,10-;/m1./s1
InChI key:InChIKey=QPAFAUYWVZMWPR-ZSOUGHPYSA-N
SMILES:C(CCC)N1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1.Cl
Synonyms:- 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)-
- 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5S)-
- Miglustat HCl
- Miglustat hydrochloride
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Found 9 products.
3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)-
CAS:Formula:C10H22ClNO4Purity:98%Color and Shape:SolidMolecular weight:255.7390(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride
CAS:<p>(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride</p>Purity:98%Color and Shape:PowderMolecular weight:255.74g/molMiglustat HCl
CAS:Formula:C10H21NO4·HClColor and Shape:White To Off-White SolidMolecular weight:219.28 36.46N-(n-Butyl)-1-deoxynojirimycin hydrochloride
CAS:<p>N-(n-Butyl)-1-deoxynojirimycin hydrochloride</p>Purity:>99%Molecular weight:255.74g/molN-Butyldeoxynojirimycin Hydrochloride
CAS:Controlled Product<p>Applications An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. N-Butyldeoxynojirimycin has recently been used to retard lipid storage in the central nervous system of an animal model of Tay-Sachs disease.1-Deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man.<br>References Hettkamp, H., et al.: Eur. J. Biochem., 142, 85 (1984), Szumilo, T., et al.: Arch. Biochem. Biophys., 247, 261 (1986), Fleet, G.W.J., et al.: FEBS Letters, 237, Number 1,2, 128 (1988), Kolter, T., et al.: Angew. Chem. Int. Ed. Engl., 36, 1955 (1997),<br></p>Formula:C10H21NO4·ClHColor and Shape:NeatMolecular weight:255.74N-Butyldeoxynojirimycin hydrochloride
CAS:<p>Competitive inhibitor of ceramide-glycosyltransferase used for substrate reduction therapy in lysosomal storage disorders. It inhibits glucosylceramide synthase, which catalyses the initial step in glycosphingolipid biosynthetic pathway. This compound delays the onset of symptoms in type 1 Gaucher disease, Sandhoff disease and Tay-Sachs disease. It also reduces brain abnormalities in mucolipidosis type IV.</p>Formula:C10H21NO4•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:255.74 g/molMiglustat hydrochloride
CAS:<p>Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher</p>Formula:C10H22ClNO4Purity:99.85%Color and Shape:SolidMolecular weight:255.74
