CAS 2101517-69-3

Formula: C23H15F8N3OS

InChI: InChI=1S/C23H15F8N3OS/c24-15-6-7-18(17(25)11-15)33-20(35)19(12-4-2-1-3-5-12)34-21(36)32-16-9-13(22(26,27)28)8-14(10-16)23(29,30)31/h1-11,19H,(H,33,35)(H2,32,34,36)/t19-/m1/s1

InChI key: BDBWQANRZRCMMD-LJQANCHMSA-N

SMILES: C1=CC=C(C=C1)[C@H](C(=O)NC2=C(C=C(C=C2)F)F)NC(=S)NC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F

BL 918

CAS: 2101517-69-3

Formula: C₂₃H₁₅F₈N₃OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 533.4369

Ref: IN-DA01E74Y

BL-918

CAS: 2101517-69-3

BL-918

Formula: C₂₃H₁₅F₈N₃OS

Purity: ≥98%

Molecular weight: 533.44

Ref: 54-BUP12611

BL-918

CAS: 2101517-69-3

BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.

Formula: C₂₃H₁₅F₈N₃OS

Purity: 99.4% - 99.89%

Color and Shape: Solid

Molecular weight: 533.44

Ref: TM-T8322

BL-918

CAS: 2101517-69-3

(R)-2-(3-(3,5-Bis(trifluoromethyl)phenyl)thioureido)-N-(2,4-difluorophenyl)-2-phenylacetamide

Formula: C₂₃H₁₅F₈N₃OS

Purity: 99%

Molecular weight: 533.44

Ref: IN-DG01204767

BL 918

CAS: 2101517-69-3

A potent small-molecule activator of UNC-51-like kinase 1 (ULK1), a serine-threonine kinase involved in autophagy. Promotes cytoprotective autophagy in MPP+-treated SH-SY5Y cells, via the ULK complex. Improves motor dysfunction and reduces loss of dopaminergic neurons, mediated by MPTP, in in vivo models of Parkinson’s disease.

Formula: C₂₃H₁₅F₈N₃OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 533.44 g/mol

Ref: 3D-BB165666

BL-918

CAS: 2101517-69-3

Purity: 99%

Color and Shape: Solid

Molecular weight: 533.081

Ref: 10-F798275

BL 918

Controlled Product

CAS: 2101517-69-3

Applications BL 918 is a potent small-molecule activator of UNC-51-like kinase 1 (ULK1), a serine-threonine kinase involved in autophagy. Promotes cytoprotective autophagy in MPP+-treated SH-SY5Y cells, via the ULK complex. Improves motor dysfunction and reduces loss of dopaminergic neurons, mediated by MPTP, in in vivo models of Parkinson’s disease.
References Ouyang, Liang., et al.: J. Med. Chem., 61, 2776 (2018),

Formula: C₂₃H₁₅F₈N₃OS

Color and Shape: Neat

Molecular weight: 533.437

Ref: TR-B595838