CAS 2101958-02-3

squarunkinA

CAS: 2101958-02-3

squarunkinA

Purity: ≥98%

Molecular weight: 523.55g/mol

Ref: 54-BUP06617

squarunkinA

CAS: 2101958-02-3

squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-

Formula: C₂₅H₃₂F₃N₅O₄

Purity: 99.29%

Color and Shape: Solid

Molecular weight: 523.55

Ref: TM-T9002

Squarunkin A

CAS: 2101958-02-3

Selective inhibitor of the interaction between the UNC119 chaperone and its cargo. Squarunkin A inhibits activation of Src kinase by interrupting the interaction between the myristoylated peptide at the N-terminus of the Src kinase and UNC119A chaperone (IC50 = 10 nM). Squarunkin A impairs the UNC119-mediated enrichment of plasma membrane with non-receptor protein tyrosine kinase Src, resulting in the decrease in Src autophosphorylation and decreased oncogenic Src signalling.

Formula: C₂₅H₃₂F₃N₅O₄

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 523.55 g/mol

Ref: 3D-BS168651