CAS 210223-32-8

(3R,4R)-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride

Description:

(3R,4R)-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride is a chemical compound characterized by its piperidine ring structure, which is a six-membered saturated nitrogen-containing heterocycle. The specific stereochemistry indicated by the (3R,4R) configuration suggests that the compound has two chiral centers, contributing to its potential biological activity and specificity in interactions with biological targets. The presence of hydroxymethyl and triol functional groups indicates that the compound has multiple hydroxyl (-OH) groups, which can enhance its solubility in water and its ability to form hydrogen bonds. As a hydrochloride salt, it is typically more stable and easier to handle than its free base form. This compound may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to its structural features that could influence its pharmacokinetics and pharmacodynamics. Its CAS number, 210223-32-8, allows for precise identification in chemical databases and literature.

Formula: C₆H₁₄ClNO₄

InChI: InChI=1/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3?,4?,5-,6-;/m1./s1

SMILES: C1C([C@H]([C@@H](C(CO)N1)O)O)O.Cl

1-Deoxy-L-idonojirimycin Hydrochloride

CAS: 210223-32-8

Formula: C₆H₁₄ClNO₄

Color and Shape: Liquid

Molecular weight: 199.6327

Ref: IN-DA002KN3

1-Deoxy-L-idonojirimycin hydrochloride

CAS: 210223-32-8

Ref: 7W-GC4019

Migalastat Impurity 5 HCl (1-Deoxy-L-idonojirimycin HCl)

CAS: 210223-32-8

Formula: C₆H₁₃NO₄

Molecular weight: 163.17

Ref: 4Z-M-249012

1-Deoxy-L-idonojirimycin Hydrochloride

Controlled Product

CAS: 210223-32-8

Stability Moisture, Temperature Sensitive
Applications An inhibitor of yeast a-glucosidase. Used in the synthesis of 1-deoxynojirimycin (DNJ), an important glycosidase inhibitor.
References Legler, G., et al.: Carbohydr. Res., 155, 119 (1986), Mitrakou, A., et al.: Diabetic Med., 15, 657 (1998), Fan, J., et al.: Nat. Med., 5, 112 (1999), Cox, T., et al.: Lancet, 355, 1481 (2000),

Formula: C₆H₁₃NO₄·ClH

Color and Shape: Neat

Molecular weight: 199.63

Ref: TR-D239750

1-Deoxy-L-idonojirimycin hydrochloride

CAS: 210223-32-8

1-Deoxy-L-idonojirimycin hydrochloride is a chaperone that is structurally related to the natural substrate, L-idonojirimycin. It has been found to interact with recombinant human Hsp70 and Hsp90. 1-Deoxy-L-idonojirimycin hydrochloride enhances the kinetic and thermodynamic parameters of these chaperones in vitro. The structural analysis of this compound revealed that it binds to both Hsp70 and Hsp90, which may be due to its ability to mimic the natural substrate's binding site on these chaperones.

Formula: C₆H₁₄ClNO₄

Purity: Min. 95%

Molecular weight: 199.63 g/mol

Ref: 3D-MD16682